: Background and Objective : To evaluate the efficacy and safety of 2 -port laparoscopic surgery for ovarian tumors and uterine leiomyomas. A conventional slip knot under laparoscopic surgery is useful, but it is difficult for beginners. Therefore, we developed new suture technique. Methods : Between January 2011 and December 2012, 38 patients underwent 2 -port total laparoscopic cystectomy (TLC) ; between January 2010 and December 2011, 45 patients underwent multiport (3 or 4 ports) TLC. Between January 2011 and December 2012, 25 patients underwent 2 -port laparoscopic myomectomy (LM) ; between January 2010 and December 2011, 34 patients underwent multiport (3 or 4 ports) LM. Surgery time, blood loss, postoperative length of stay and complications were retrospectively compared in each group. Results : No significant differences in surgery time, blood loss or postoperative length of stay were found between 2 -port TLC and multiport TLC. No significant differences were found in the aforementioned parameters between 2 -port LM and multiport LM. We showed here a new suture technique 'intra -abdominal suturing/extra -abdominal traction method' instead of conventional slip knot. Conclusions : We confirmed that 2 -port TLC and LM are less invasive than conventional multiport laparoscopic surgery ; furthermore, they are as safe as the conventional procedure. The new suture technique is easier than conventional slip knot and can applies sufficient tension to the suture knot for beginners.