Single Fluorescent Probe Displays a Distinct Response to Zn²⁺ and Cd²⁺

Abstract

Single probe, multiple targets: the design and synthesis of a new probe is described that can readily discriminate Zn(2+) and Cd(2+) with different fluorescence signals. The studies of Job's plot, mass spectroscopy, DFT calculations, and (1)H NMR spectroscopy reveal that the new probe has possible distinct binding modes to Zn(2+) and Cd(2+). This work may open up new opportunities for the development of single fluorescent probes that can sense multiple targets of interest.

Reversible “OFF–ON” fluorescent and colorimetric sensor based benzothiazole-bisphenol A for fluoride in MeCN

“…This is probably due to high negative charge density on F -which14 induces the strong hydrogen bonding with OH in BBA. The formation of these hydrogen15 bonds affects the electronic properties of the chromophore, concluding a color change with a 16 subsequent new intraligand or internal charge transfer (ICT) band 17. The fluorescence behavior of BBA was observed in the presence of various anions 18(Fig.…”

“…of F -), which is produced by the stronger basicity of OH − than F − in 12 leading to the deeper deprotonation [35]. 14 The reversibility of a chemosensor is one of the essential aspects for sensor 15 applications. Therefore, the reversibility of BBA was observed by the alternate addition of F - 16 and calcium perchlorate (Ca(ClO 4 ) 2 ).…”

“…Anion-sensing properties of BBA15 The anion binding affinities of BBA were investigated in the presence of various16 anions (F -, Br -, Cl -, I -, AcO -using UV-vis and 17 fluorescence spectroscopy in MeCN solution at 5.0 μM concentration because the receptors 18 with the imine and phenol groups sometimes showed the sensing properties of anions [30, 19 31]. Fig.1a shows the UV-vis spectral changes of BBA in the presence of F -anion with 20 different concentrations.…”

A Quinoline-Based Ratiometric and Reversible Fluorescent Probe for Cadmium Imaging in Living Cells

“…To the best of our knowledge, several fluorescent probes for cadmium have been reported. [13][14][15][16][17][18] In these probes, however, their practical application is still limited as their poor water solubility (need more than 30% organic solvent as co-solution) or need complicated synthesis steps to obtain these probes. Many of these probes can not reduce the fluorescence interference of Zn 2+ due to the similar coordination properties of Zn 2+ and Cd 2+ .…”

A turn-on Schiff-base fluorescence sensor for Mg 2+ ion and its practical application

“…Among the various types of sensors, fluorescence sensors are excellent tools for detecting metal ions due to their high sensitivity, good selectivity and easy operation [2][3][4]. Magnesium (Mg 2 þ ) is the fourth most abundant metal in our body.…”