“…Individual aztreonam concentrations and relevant covariates (age, weight, height, serum creatinine concentration) were obtained from 2 aztreonam clinical studies in healthy male volunteers with normal renal function or various degrees of renal impairment. In the study by Mihindu et al, 24 male volunteers were included, and plasma samples were collected 0.16, 0.33, 0.5, 1, 2, 3, 4, 6, 8, 12, 24, and 48 hours after dosing.…”