Single cell spatial profiling of FFPE splenic tissue from a humanized mouse model of HIV infection
Guoxin Wu,
Samuel H. Keller,
Luca Sardo
et al.
Abstract:Background
Latency remains a major obstacle to finding a cure for HIV despite the availability of antiretroviral therapy. Due to virus dormancy, limited biomarkers are available to identify latent HIV-infected cells. Profiling of individual HIV-infected cells is needed to explore potential latency biomarkers and to study the mechanisms of persistence that maintain the HIV reservoir.
Methods
Single cell spatial transcriptomic characterization using … Show more
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