Abstract:Single-cell RNA sequencing ("scRNA-Seq") examines the cell population at the single-cell level. The single cell changes in the osteoimmunological microenvironment in fresh and old fractures have not been studied. We used single cell transcriptomics in this study to uncover differences in the molecular composition and cellular signaling in bone tissue from fresh and old fractures.We first searched for and downloaded single-cell omics data from the GEO database, which included both fresh and old fracture samples… Show more
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