2020
DOI: 10.21203/rs.3.rs-74172/v1
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Single-cell Profiling Reveal Types of Interstitial Cells in Human and Rat Bladder

Abstract: Backgrounds:The mechanism underlying bladder urination pathophysiologies has not been understood yet because the types of interstitial cells present in the bladder are still obscure. Results:Here, we classified the cell types in the bladder without bias using 10x genomics single-cell RNA-seq and identified 35,510 and 19,946 cells from human and rat bladder tissues, respectively. In addition to the major cell clusters including urothelial cells, smooth muscle cells, endothelial cells, neurons, and immune cells,… Show more

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