Single cell discovery of m6A RNA modifications in the hippocampus
Shuangshuang Feng,
Maitena Tellaetxe-Abete,
Yujie Zhang
et al.
Abstract:N6-methyladenosine (m6A) is a prevalent and highly regulated RNA modification essential for RNA metabolism and normal brain function. It is particularly important in the hippocampus, where m6A is implicated in neurogenesis and learning. Although extensively studied, its presence in specific cell types remain poorly understood. We investigated m6A in the hippocampus at the single cell level, revealing a comprehensive landscape of m6A modifications within individual cells. Our data also identifies transcripts wh… Show more
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