2018
DOI: 10.1016/j.pdpdt.2018.01.001
|View full text |Cite
|
Sign up to set email alerts
|

Single and combined effects of photodynamic therapy and antibiotics to inactivate Staphylococcus aureus on skin

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

2
29
0

Year Published

2018
2018
2024
2024

Publication Types

Select...
8

Relationship

0
8

Authors

Journals

citations
Cited by 48 publications
(44 citation statements)
references
References 58 publications
2
29
0
Order By: Relevance
“…The direct comparison of in vitro results with results of the porcine skin clearly show that killing of bacteria on the skin requires a higher photosensitizer concentration and radiant exposure, obviously to overcome some unexplored obstacles, which is partially comparable with other studies . This is a crucial point for future clinical application of PIB against bacteria on skin.…”
Section: Discussionsupporting
confidence: 67%
See 2 more Smart Citations
“…The direct comparison of in vitro results with results of the porcine skin clearly show that killing of bacteria on the skin requires a higher photosensitizer concentration and radiant exposure, obviously to overcome some unexplored obstacles, which is partially comparable with other studies . This is a crucial point for future clinical application of PIB against bacteria on skin.…”
Section: Discussionsupporting
confidence: 67%
“…A recent paper likewise showed very promising results in an ex vivo skin model using a porphyrin as photosensitizer. In the study a reduction of about 4 log 10 steps of S. aureus was achieved, and even more than 5 log 10 steps when combining PIB with the antibiotic substance ampicillin …”
Section: Discussionmentioning
confidence: 86%
See 1 more Smart Citation
“…A probable explanation is that the singlet oxygen and/or other ROS produced by the PSs which are interacting with the membranes are involved in photoperoxidation, which is responsible for the membrane damage, highlighting the paired selectivity (light and PS cellular localization) [11]. One of the most impressive facts is that aPDT is efficient in multidrug-resistant strains and does not encourage resistance [12]; the repeated photosensitization of surviving cells does not induce the selection of resistant microbial strains and does not modify their sensitivity to antibiotic treatment [13][14][15].…”
Section: Introductionmentioning
confidence: 99%
“…chloramphenicol) or enhance the efficacy of antibiotics targeting the external structure of bacteria (e.g. ampicillin) [76].…”
Section: Staphylococcus Aureusmentioning
confidence: 99%