SINGLE-01: a randomized, controlled trial comparing the efficacy and depth of insertion of single- and double-balloon enteroscopy by using a novel method to determine insertion depth

Efthymiou, Marios; Desmond, Paul; Nauze, Richard La; Kaffes, Arthur J.; Chua, Tee Joo; Taylor, Andrew

doi:10.1016/j.gie.2012.06.033

Cited by 78 publications

(86 citation statements)

References 21 publications

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“…The results of these RTCs tended to reveal a better diagnostic and therapeutic yield of DBE than SBE, even though they did not find statistical significance 4–7. However, previous RCTs were performed by less experienced endoscopists in SBE, compared to DBE 4,5,7. Although both DBE and SBE adopted the push and pull technique, the instruments used and technique details are different.…”

Section: Introductionmentioning

confidence: 95%

Comparison of the Efficacy and Safety of Single-versus Double-Balloon Enteroscopy Performed by Endoscopist Experts in Single-Balloon Enteroscopy: A Single-Center Experience and Meta-Analysis

Kim

Chang

et al. 2017

Gut and Liver

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Background/AimsStudies concerning the efficacy and safety of single-balloon enteroscopy (SBE) compared with that of double-balloon enteroscopy (DBE) often appear to be conflicting. However, previous studies were performed by endoscopists who were less experienced in SBE compared with DBE.MethodsWe performed a retrospective analysis of SBE and DBE data performed by a single enteroscopist, with expertise in SBE, using a prospective balloon-assisted enteroscopy registry from 2013 to 2015. Furthermore, we performed a comprehensive literature search and meta-analysis of available studies, including the current study, to clarify the efficacy and safety of SBE versus DBE.ResultsA total of 65 procedures in 44 patients with SBE and 74 procedures in 69 patients with DBE were analyzed. There were no significant differences in diagnostic yield (61.1% vs 77.3%, respectively, p=0.397), therapeutic yield (39.1% vs 31.8%, respectively, p=0.548), and complication rate (4.4% vs 2.3%, p=1.000). In the meta-analysis, which included four randomized controlled trials and three observational studies, there were no significant differences in the pooled relative risk and odds ratio for diagnostic and therapeutic yield and complications of SBE compared with those of DBE.ConclusionsThe performance of SBE appears to be similar to that of DBE in terms of diagnostic and therapeutic yield and complications.

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Section: Introductionmentioning

confidence: 95%

Comparison of the Efficacy and Safety of Single-versus Double-Balloon Enteroscopy Performed by Endoscopist Experts in Single-Balloon Enteroscopy: A Single-Center Experience and Meta-Analysis

Kim

Chang

et al. 2017

Gut and Liver

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“…SBE has a single balloon at tip of overtube and has similar diagnostic and therapeutic yield [120]. The complete visualization is possible in 11% of the patients, in contrast to 18% in DBE [121].…”

Section: Management Of Small Bowel Bleedmentioning

confidence: 99%

Small bowel bleeding: a comprehensive review

Gunjan

Sharma

Bhasin

2014

Gastroenterology Report

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The small intestine is an uncommon site of gastro-intestinal (GI) bleeding; however it is the commonest cause of obscure GI bleeding. It may require multiple blood transfusions, diagnostic procedures and repeated hospitalizations. Angiodysplasia is the commonest cause of obscure GI bleeding, particularly in the elderly. Inflammatory lesions and tumours are the usual causes of small intestinal bleeding in younger patients. Capsule endoscopy and deep enteroscopy have improved our ability to investigate small bowel bleeds. Deep enteroscopy has also an added advantage of therapeutic potential. Computed tomography is helpful in identifying extra-intestinal lesions. In cases of difficult diagnosis, surgery and intra-operative enteroscopy can help with diagnosis and management. The treatment is dependent upon the aetiology of the bleed. An overt bleed requires aggressive resuscitation and immediate localisation of the lesion for institution of appropriate therapy. Small bowel bleeding can be managed by conservative, radiological, pharmacological, endoscopic and surgical methods, depending upon indications, expertise and availability. Some patients, especially those with multiple vascular lesions, can re-bleed even after appropriate treatment and pose difficult challenge to the treating physician.

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“…Single balloon enteroscope has a single balloon at the tip of over tube and has similar diagnostic and therapeutic yield as in DBE. Single balloon enteroscopy is safe with low complication rate (Efthymiou M, 2012). The main pitfall of SBE is incomplete visualization of small bowel.…”

Section: Introduction:-mentioning

confidence: 99%

Large Jejunal Av Malformation With Intestinal Ascariasis Presenting as Obscure Gastrointestinal Bleed.

Sodhi¹,

Kawoosa²,

Shaista³

et al. 2017

IJAR

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SINGLE-01: a randomized, controlled trial comparing the efficacy and depth of insertion of single- and double-balloon enteroscopy by using a novel method to determine insertion depth

Cited by 78 publications

References 21 publications

Comparison of the Efficacy and Safety of Single-versus Double-Balloon Enteroscopy Performed by Endoscopist Experts in Single-Balloon Enteroscopy: A Single-Center Experience and Meta-Analysis

Comparison of the Efficacy and Safety of Single-versus Double-Balloon Enteroscopy Performed by Endoscopist Experts in Single-Balloon Enteroscopy: A Single-Center Experience and Meta-Analysis

Small bowel bleeding: a comprehensive review

Large Jejunal Av Malformation With Intestinal Ascariasis Presenting as Obscure Gastrointestinal Bleed.

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