Síndrome RS3PE asociado a amiloidosis primaria y mieloma múltiple, con cuadro de seudobstrucción intestinal

Remitting Seronegative Symmetrical Synovitis with Pitting Edema Syndrome Associated with Myeloma and Syndrome of Inappropriate Antidiuretic Hormone Secretion in an Elderly Man

“…Several cases of RS3PE associated with cancers, mainly solid cancers, including prostatic, gastric, and colonic adenocarcinomas, have been described . Some cases of RS3PE associated with hemopathy, particularly non‐Hodgkin's lymphoma, myelodysplasia, and chronic lymphocytic leukemia, have also been reported, but only two cases of RS3PE associated with myeloma had been reported in elderly adults . In individuals with paraneoplastic RS3PE, general signs such as general weakness or febricula are frequent, which is not the case in nonparaneoplastic RS3PE.…”

“…This is the first reported case of an association between RS3PE, myeloma, and SIADH. Few cases of associations between RS3PE and myeloma and between SIADH and myeloma have been reported, and to the knowledge of the authors, there have been no reports associating the three diagnoses.…”

“…To the Editor : Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) and the syndrome of inappropriate antidiuretic hormone secretion (SIADH) can be related to neoplasia, but the association between each of these syndromes and myeloma is rare, particularly in elderly adults . A case of RS3PE associated with myeloma and SIADH is reported herein.…”