Síndrome mascarada por retinoblastoma difuso

Català‐Mora, Jaume; A, Parareda-Salles; Vicuña-Muñoz, C.G.; Medina-Zurinaga, M.; Prat-Bartomeu, Joan

doi:10.4321/s0365-66912009000900008

Cited by 4 publications

(1 citation statement)

References 2 publications

(4 reference statements)

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“…BCR is a chronic, bilateral, and posterior uveitis that has an almost 100% genetic association with HLA-A29 [8]. Uveitis or uveitis masquerade syndrome could also be induced by some intraocular tumors, such as retinoblastoma and intraocular lymphoma, or their therapeutic approaches [9,10,11,12,13,14,15]. …”

Section: Introductionmentioning

confidence: 99%

Determination of Genes Related to Uveitis by Utilization of the Random Walk with Restart Algorithm on a Protein–Protein Interaction Network

Yan

et al. 2017

IJMS

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Uveitis, defined as inflammation of the uveal tract, may cause blindness in both young and middle-aged people. Approximately 10–15% of blindness in the West is caused by uveitis. Therefore, a comprehensive investigation to determine the disease pathogenesis is urgent, as it will thus be possible to design effective treatments. Identification of the disease genes that cause uveitis is an important requirement to achieve this goal. To begin to answer this question, in this study, a computational method was proposed to identify novel uveitis-related genes. This method was executed on a large protein–protein interaction network and employed a popular ranking algorithm, the Random Walk with Restart (RWR) algorithm. To improve the utility of the method, a permutation test and a procedure for selecting core genes were added, which helped to exclude false discoveries and select the most important candidate genes. The five-fold cross-validation was adopted to evaluate the method, yielding the average F1-measure of 0.189. In addition, we compared our method with a classic GBA-based method to further indicate its utility. Based on our method, 56 putative genes were chosen for further assessment. We have determined that several of these genes (e.g., CCL4, Jun, and MMP9) are likely to be important for the pathogenesis of uveitis.

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Section: Introductionmentioning

confidence: 99%

Determination of Genes Related to Uveitis by Utilization of the Random Walk with Restart Algorithm on a Protein–Protein Interaction Network

Yan

et al. 2017

IJMS

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Pediatric Pars Planitis: A Review

Khochtali,

Ozdal,

AlBloushi

et al. 2023

Ocular Immunology and Inflammation

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Clinical characteristics and differential diagnosis of retinoblastoma

Bahriddinova¹,

Исламов²

2012

MHSJ

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The purpose of our work was to analyze the clinical presentation of patients with retinoblastoma who were admitted to ocular oncology department on different stages of the neoplastic process. There were hospitalized 369 children with diagnosis of retinoblastoma to ocular oncology department of National Oncology Center of between 2001 and 2011, on age from 1 month to 11 years. We have analyzed the case reports and outpatient clinical records of these patients. Taking into account the variability of clinical presentation the early case finding, examination and adequate treatment of patients with retinoblastoma is a pressing challenge. That is why it has to be performed in big centers with available modern equipment and qualified specialists, who can adequately interpret the examination results and timely perform the necessary treatment.

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Síndrome mascarada por retinoblastoma difuso

Cited by 4 publications

References 2 publications

Determination of Genes Related to Uveitis by Utilization of the Random Walk with Restart Algorithm on a Protein–Protein Interaction Network

Determination of Genes Related to Uveitis by Utilization of the Random Walk with Restart Algorithm on a Protein–Protein Interaction Network

Pediatric Pars Planitis: A Review

Clinical characteristics and differential diagnosis of retinoblastoma

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