Síndrome del nevo de Becker

Síndrome do nevo de Becker

“…[1][2][3] Spontaneous regression of the lesion may occur. In 1984, Person and Longcope detected an increase in androgen receptor levels in Becker's nevus.…”

“…1,2 In the past, many authors have observed the association between BN and other disorders such as breast hypoplasia or scoliosis. 1 However, it was only in 1995 that the term hairy epidermal nevus syndrome or Becker nevus syndrome was described for the first time by Happle as an association of BN with unilateral breast hypoplasia and muscle, skin and/or skeletal abnormalities.…”

Síndrome do nevo de Becker: relato de caso

“…1 Since then various cases have been described in the medical literature including reports of multiple or bilateral cases. 4,5 In 1981, Tymen et al estimated a prevalence of 0,5% in young (age varying from 17 to 26 years) male patients. 2 The proportion between the male and female sexes has been already described as 2:1.…”

“…The dermis can present a superficial and perivascular lympho-histiocytic infiltrate and melanophages can be seen in the papillary dermis. 5,6 In some cases it is found hyperplasia of smooth muscle fibers arranged in a disorganized way in the reticular dermis, Baeta IGR, Viotti CV, Pereira ACF, Costa SR Jr, Bittencourt FV corresponding to a hamartoma. 4,7 The majority of the authors attribute an spectral concept to the Becker's nevus and to the smooth muscle hamartoma.…”

“…4 It is also considered the hypothesis of a hormone-dependent disorder based on the increase of the number of androgen-receptors in the affected areas, that would explain the appearing of lesions in puberty and alterations such as hyper trichosis and acneform eruptions restricted to the affected regions. 5 The differential diagnosis includes post-inflammatory hyperpigmentation ,congenital melanocytic nevus, congenital hamartoma of smooth muscle fibers and spots of white coffee colour.…”