Síndrome de distrés respiratorio agudo: revisión a propósito de la definición de Berlín

Cabezón, Nekari de Luis; Castro, Ixchel; Uriarte, U.X. Bengoetxea; Casanova, Mauricio Phélan; Peña, J.M. García; Celorrio, L. Aguilera

doi:10.1016/j.redar.2014.02.007

Cited by 12 publications

(7 citation statements)

References 46 publications

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“…Si bien, la frecuencia de diagnóstico del SDRA podría no parecer alarmante, las cifras referidas a la mortalidad son muy elevadas, oscilando entre el 26-58% y en algunos casos superando el 80%. 1,26,27 En centros de excelencia se reporta mortalidad del 30%. No obstante, debe considerarse que sólo el 5% de los pacientes afectados por el SDRA fallecen de la insuficiencia respiratoria aguda, el resto lo hace por la disfunción múltiple de órganos, siendo los factores más fuertemente asociados con dicha mortalidad dependientes de las enfermedades de base y de la intensidad de la respuesta biológica a la misma.…”

Section: Discussionunclassified

“…y fisiopatología son complejas y forman parte de cuadros clínicos con lesiones de otros órganos y sistemas. 1 La terapéutica del mismo resulta compleja; aunque de modo general se enmarca en pilares tales como: resucitación cardiopulmonar y estabilización de la oxigenación, identificación y rápida eliminación de la causa que produjo la lesión pulmonar, así como el logro de un adecuado transporte de oxígeno a los tejidos y otros órganos, y en la prevención, diagnóstico y tratamiento de las posibles complicaciones. 1,2 En el ámbito internacional existen evidencias incuestionables en la disminución de la incidencia y severidad del SDRA cuando se emplea en el tratamiento un surfactante exógeno, ya que al disminuir la tensión superficial en la…”

Section: Resumen Objetivounclassified

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Evaluación de la seguridad del uso poscomercial del surfactante cubano, SURFACEN<sup>®</sup>, en el tratamiento del síndrome de dificultad respiratoria aguda del adulto

Pérez

Alonso

Casañas

et al. 2019

NCT Neumología Y Cirugía De Tórax

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Section: Discussionunclassified

Section: Resumen Objetivounclassified

Evaluación de la seguridad del uso poscomercial del surfactante cubano, SURFACEN<sup>®</sup>, en el tratamiento del síndrome de dificultad respiratoria aguda del adulto

Pérez

Alonso

Casañas

et al. 2019

NCT Neumología Y Cirugía De Tórax

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“…The diagnosis is made according to overhydration. 14 The following are considered: sudden onset of respiratory tract symptoms, signs of lung oedema in imaging tests (not caused by cardiac diseases or effusion) and hypoxemia. In most cases of COVID-19, there is diffused injury of pulmonary alveoli.…”

Section: Ards -A Severe Coursementioning

confidence: 99%

Pulmonary complications due to COVID-19 – a literature review

Romaszko-Wojtowicz

Doboszyńska

2021

Pol. Ann. Med.

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Introduction: irst cases of a disease called coronavirus disease 2019 (COVID-19), caused by a novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of the coronavirus family, were detected in December 2019. The disease is manifested by a variety of symptoms and can run a different course: from oligosymptomatic or asymptomatic to the development of acute respiratory failure and even death. Aim: The aim of this paper is to provide critical analysis of the potential pulmonary complications after COVID-19 infection. Material and methods: We have provided the systematic literature review based on which we have discussed the pathophysiology of COVID-19, its outcomes, risk factors and pulmonary complications. Results and discussion: The organs that are most often affected by a SARS-CoV-2 infection are the lungs. An infection with this virus can lead to a severe respiratory tract illness, both in the acute phase and as a complication after a relatively mild case. There are numerous observations of patients convalescing from COVID-19 who suffer from the interstitial pulmonary disease with fibrosis. There are also reported cases of spontaneous pneumothorax after COVID-19. Conclusions: It should be borne in mind that other late complications may appear with time.

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“…However, although VATS is less damaging, one-lung ventilation (OLV), which is required for most of the procedures, can also contribute to the development of ALI [ 4 ]. ALI and ARDS are parts of the same disease spectrum [ 5 , 6 ], which includes pulmonary edema as the intrinsic pathologic process; acute lung injury after pulmonary resection has thus been variously described as post-lung resection pulmonary edema, postpneumonectomy pulmonary edema, and low pressure or noncardiogenic pulmonary edema [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Endothelial Glycocalyx Layer: A Possible Therapeutic Target for Acute Lung Injury during Lung Resection

Wang

2017

BioMed Research International

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Background Shedding of the endothelial glycocalyx layer (EGL) is known to occur during major surgery, but its degradation associated with minimally invasive video-assisted thoracoscopy (VATS) remains unclear. We investigated if serum biomarkers of EGL disruption were elevated during VATS lobectomy, and whether the urinary trypsin inhibitor (UTI) ulinastatin exerted a protective effect during this procedure. Materials and Methods Sixty ASA II-III lung cancer patients undergoing elective VATS lobectomy were divided equally into UTI and control groups. UTI group patients received intravenous UTI during surgery. Serum levels of syndecan-1 and heparan sulfate were examined before (T0) and at the end of surgery (T1). Serum albumin and hemoglobin were measured before surgery (BOD) and on the first postoperative day (POD1). Results In control group, syndecan-1 levels were significantly elevated at T1 compared with T0 (3.77 ± 3.15 versus 4.28 ± 3.30, P = 0.022⁎) and increased even more significantly in patients whose surgery lasted >3 h (3.28 ± 2.84 versus 4.31 ± 3.39, P = 0.003⁎⁎). Serum albumin levels on POD1 were significantly lower in control group compared with UTI group (32.63 ± 4.57 versus 35.76 ± 2.99, P = 0.031⁎). Conclusion EGL degradation occurs following VATS lobectomy. UTI can alleviate this shedding, thus helping preserve normal vascular permeability. Trail Registration This trial is registered with ChiCTR-IOC-17010416 (January 13, 2017).

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Síndrome de distrés respiratorio agudo: revisión a propósito de la definición de Berlín

Cited by 12 publications

References 46 publications

Evaluación de la seguridad del uso poscomercial del surfactante cubano, SURFACEN<sup>®</sup>, en el tratamiento del síndrome de dificultad respiratoria aguda del adulto

Evaluación de la seguridad del uso poscomercial del surfactante cubano, SURFACEN<sup>®</sup>, en el tratamiento del síndrome de dificultad respiratoria aguda del adulto

Pulmonary complications due to COVID-19 – a literature review

Endothelial Glycocalyx Layer: A Possible Therapeutic Target for Acute Lung Injury during Lung Resection

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