Sindrom khronicheskoy ustalosti: sovremennye predstavleniya ob etiologii

Pigarova, E A; Плещева, А В; Дзеранова, Л. К.; Ya, Rozhinskaya L

doi:10.14341/2071-8713-4977

Cited by 5 publications

(2 citation statements)

References 39 publications

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“…Пациенты, страдающие СХУ, часто функционируют со значительно меньшей степенью активности, чем они были способны до болезни. Этиология заболевания до сих пор не определена, несмотря на предложение нескольких теорий его возникновения [2], и нет конкретных диагностических тестов, поэтому современная диагностика СХУ основывается на трех критериях, представленных в таблице 1.…”

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“…Распространенность СХУ в популяции, по разным оценкам, может достигать 2%, а это примерно 120-140 миллионов человек в мире, однако, по оценкам некоторых авторов, только у 16% пациентов диагноз СХУ устанавливается и назначается лечение [2,3]. Все расы и этнические группы подвержены СХУ, но чаще им страдают лица женского пола с пиком заболеваемости в возрасте 40-60 лет [3,4,5].…”

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Chronic fatigue syndrome in middle-aged women: the role of disorders of glucose metabolism

Anastasiya¹,

Aleksamdrovna²,

Константиновна³

2014

Obes. metabol.

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Objectives: To determine the prevalence of chronic fatigue syndrome (CFS) among middle-aged women and to assess the role of glucose metabolism disturbances in the development of this pathology. Materials and Methods: The study included 231 women from 40 to 60 years old (mean age 52.3 ± 5 years), observed at urban polyclinic in Moscow, who was referred to or was observed by an endocrinologist (n = 142, group 1), therapist (n = 56, group 2) or had a prophylactic medical examinations (n = 33, group 3). We recorded demographic and anthropometric data, accessed levels of glucose, glycated hemoglobin, insulin and calculated BMI and HOMA indexes. Results: The prevalence of CFS in the whole group of patients studied was 27%. The highest frequency of CFS is registered in the group of patients observed by the endocrinologist – 35%, and at dispensary examination – 21%, which was significantly different from the prevalence of CFS in patients seeking an appointment with a therapist – 13% (p = 0.002 and p = 0.03 for Fisher's exact test, respectively). Higher BMI, blood glucose, glycosylated hemoglobin, and HOMA insulin resistance index as naturally expected were observed in group 1, but after further division for the presence or absence of CFS, significant differences for patients with CFS were only higher fasting glucose levels in group 2. Conclusions: We determined the prevalence of CFS in the examined groups of patients and showed only a weak correlation of CFS and disturbances of glucose metabolism.

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Chronic fatigue syndrome in middle-aged women: the role of disorders of glucose metabolism

Anastasiya¹,

Aleksamdrovna²,

Константиновна³

2014

Obes. metabol.

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Pharmacological treatment of patients with chronic fatigue syndrome

Глазачев

Дудник

Zagaynaya

2017

Z. nevrol. psikhiatr. im. S.S. Korsakova

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The EG patients showed a significant reduction in the index of chronic fatigue, which was accompanied by the significant decrease in state depression, anxiety, improvements in subjective assessment of quality of life, as well as a significant increase in physical performance indices (maximal oxygen consumption, anaerobic threshold, load time to failure, normalization of the lipid 'profile' immediately after course of infusions and in 5 weeks follow-up). No changes in chronic fatigue index and other recorded indicators were identified in CG. Laennec did not cause side effects, was well tolerated by all patients.

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