Sind elektive Lymphknotendissektionen in der Karzinomchirurgie noch zeitgemäß?

Hölzel, Dieter; Engel, Jay; Löhrs, U.

doi:10.1055/s-0028-1098738

Cited by 19 publications

(8 citation statements)

References 28 publications

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“…Up to now there is no meta-analysis consistent randomized study for any tumor (LoE 1A study) that confirms the prognostic benefit of elective lymph node dissection [131]. An extensive review article analyses the significance of lymphadenectomy in solid tumors and revealed that lymph node dissection does not lead to a significant improvement of the total survival [132].…”

Section: Prognostic Relevance Of Neck Dissectionmentioning

confidence: 99%

Current advances in diagnosis and surgical treatment of lymph node metastasis in head and neck cancer

Teymoortash,

Werner

2012

GMS Current Topics in Otorhinolaryngology - Head and Neck Surgery; 11:Doc04; ISSN 1865-1011

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Section: Prognostic Relevance Of Neck Dissectionmentioning

confidence: 99%

Current advances in diagnosis and surgical treatment of lymph node metastasis in head and neck cancer

Teymoortash,

Werner

2012

GMS Current Topics in Otorhinolaryngology - Head and Neck Surgery; 11:Doc04; ISSN 1865-1011

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“…Wenn die Metastasen nicht metastasieren und sich unabhängig von ihrem Primärtumor entwickeln, stellt sich die Frage, ob bei Kopf-Hals-Karzinomen die Neck dissection das Risiko für die hä-matogene Metastasierung und die Prognose der betroff enen Patienten beeinfl ussen kann. Es gibt zurzeit zu keinem Tumor eine Metaanalyse konsistente randomisierte Studie (LoE 1 A-Studie), die den prognostischen Nutzen der elektiven Lymphknotendissection belegt [ 131 ] . Eine ausführliche Übersichtsarbeit analysierte die Bedeutung der Lymphadenektomie bei soliden Tumoren und stellte fest, dass Lymphknotendissection keine signifikante Verbesserung der Gesamtüberlebensrate bewirken kann [ 132 ] .…”

Section: Prognostische Bedeutung Von Neck Dissection ▼unclassified

Aktuelle Fortschritte in der Diagnostik und chirurgischen Therapie der Halslymphknotenmetastasen bei Kopf-Hals-Karzinomen

Teymoortash

Werner

2012

Laryngo-Rhino-Otol

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Still today, the status of the cervical lymph nodes is the most important prognostic factor for head and neck cancer. So the individual treatment concept of the lymphatic drainage depends on the treatment of the primary tumor as well as on the presence or absence of suspect lymph nodes in the imaging diagnosis. Neck dissection may have either a therapeutic objective or a diagnostic one. The selective neck dissection is currently the method of choice for the treatment of patients with advanced head and neck cancers and clinical N0 neck. For oncologic reasons, this procedure is generally recommended with acceptable functional and aesthetic results, especially under the aspect of the mentioned staging procedure. In this review article, current aspects on pre- and posttherapeutic staging of the cervical lymph nodes are described and the indication and the necessary extent of neck dissection for head and neck cancer is discussed. Additionally the critical question is discussed if the lymph node metastasis bears an intrinsic risk of metastatic development and thus its removal in a most possible early stage plays an important role.

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“…Auch in der chirurgischen Literatur wird von Einzelnen eine "radikale" Lymphknotendissektion abgelehnt, ohne dass Gründe genannt werden oder obwohl sogar aus den eigenen Daten der Autoren eindeutig Argumente für eine radikale Lymphknotendissektion abzuleiten wären [10,23].…”

Section: Argumente Gegen Eine Lymphknotendissektionunclassified

Lymphknotendissektion bei Karzinomen des unteren Gastrointestinaltraktes

Hohenberger

Lux

Merkel

et al. 2011

Chirurg

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Evidence-based analysis of the influence of lymph node dissection on the prognosis of colorectal cancer patients is complicated by the now well-established multimodal treatment strategies. In addition surgical quality criteria, such as exact preparation along the mesenterial fascia and avoiding tears have a major influence on the prognosis.Nevertheless, the overall evidence for the need of lymph node dissection in the treatment of colorectal carcinoma is high. However, there are still some questions remaining concerning the extent of pericolic lymph node dissection, inclusion of the lymph nodes along the greater curvature of the stomach and the inferior aspect of the left pancreas in carcinomas of the transverse colon and the flexures. In particular the definitive central ligation of the supplying arteries in right-sided colon carcinoma is not adequately implemented worldwide.

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Sind elektive Lymphknotendissektionen in der Karzinomchirurgie noch zeitgemäß?

Cited by 19 publications

References 28 publications

Current advances in diagnosis and surgical treatment of lymph node metastasis in head and neck cancer

Current advances in diagnosis and surgical treatment of lymph node metastasis in head and neck cancer

Aktuelle Fortschritte in der Diagnostik und chirurgischen Therapie der Halslymphknotenmetastasen bei Kopf-Hals-Karzinomen

Lymphknotendissektion bei Karzinomen des unteren Gastrointestinaltraktes

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