Simultaneously improving the resolving power and sensitivity for planar high‐field asymmetric waveform ion mobility spectrometry using a mixed gas inlet mode at two ends
Abstract:Rationale
Resolution and sensitivity are two key parameters for describing the performance of high‐field asymmetric waveform ion mobility spectrometry (FAIMS). An increase in the resolving power of FAIMS has been realized by adding helium to nitrogen in planar FAIMS, but it comes at the expense of sensitivity.
Methods
Here, a new hollow needle‐to‐ring discharge device integrated on a PCB substrate is used as the ion source for FAIMS. Helium flows from the hollow part of the hollow needle to improve the ionizat… Show more
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