Simultaneously Diagnosed Autoimmune Hepatitis Type II, Grave’s Disease and Congenital Factor VII Deficiency

Abstract

Autoimmune hepatitis (AIH) is progressive, chronic immunologically mediated inflammatory liver disorder that occurs in children and adults of all ages, predominantly in women. AIH can be combined with other autoimmune and non-autoimmune conditions. We present a case of a 32 year-old female with three relatively uncommon diseases -two autoimmune diseases and one inherited, making their combination even more rare.

Congenital Factor VII Deficiency in Association With Bicuspid Aortic Valve and Multicystic Dysplastic Kidney Disease in a Child

“…In the contrary, combined protein C deficiency and congenital factor VII deficiency has been described in a single study [15], the gene for protein C is encoded in chromosome 2, hence the combination of both is random. A number of studies listed in Table 2 [9,13,[15][16][17][18][19][20][21][22][23][24][25][26][27][28][29] have shown unique combinations of factor VII deficiency and different associations with no evident explanation.…”