Simultaneous toxicokinetic studies of aristolochic acid I and II and aristolactam I and II using a newly-developed microdialysis liquid chromatography-tandem mass spectrometry

Quantum Dot-Based Immunoassays: Unraveling Sensitivity Discrepancies and Charting Future Frontiers

“…It is therefore paramount to develop precise methodologies for the detection and quantification of AAs (Figure B). Specifically, among the various compounds within the aristolochic acid family, aristolochic acid I (AAI) and aristolochic acid II (AAII) stand out as the primary chemical constituents, , with AAI exhibiting notably higher nephrotoxic and carcinogenic properties . This rationale informs our choice of AAI as the primary target compound with the objective of facilitating the rapid screening of AAI in large quantities of food and pharmaceuticals.…”