Simultaneous Specific Demonstration of Thyrotroph, Gonadotroph and Acidophil Cells in the Anterior Hypophysis

Paget, Graham; Eccleston, E

doi:10.3109/10520296009114726

Cited by 35 publications

(7 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Consecutive sections stained with the AF, PAS/ OG/MB or trichrome methods identified the blue-black cells as delta 1 cells, purple cells as delta 2 cells and red cells as beta and zeta cells. Therefore, it is obvious that AT stained the delta 1 and delta 2 cells selectively but did not stain the zeta and beta cells in the pars distalis of the sheep, in contrast with the descriptions of PAGET and ECCLESTON (1960) and of EZRIN and MURRAY (1963).…”

Section: Histochemical Observationmentioning

confidence: 66%

“…It was identified that the PAS red cells were zeta and beta cells and that the PAS-purple cells were delta 1 and delta 2 cells. PAGET and ECCLESTON (1960), using aldehyde-thionin method combined with PAS and fast blue, differentiated blue-black thyrotrophs, red gonadotrophs and green acidophils in the adenohypophysis of the rat and dog. EZRIN and MURRAY (1963) identified seven separate cell types in the human pars distalis by the AT/PAS/ OG method and described that AT stained beta 2 and delta 1 cells selectively.…”

Section: Histochemical Observationmentioning

confidence: 99%

“…Recently, the alcian blue (HERLANT and RACADOT, 1957) and aldehyde-thionin (PAGET and ECCLESTON, 1959) were also found to be useful in the differential staining of basophil cell types. None of these staining methods is, however, wholly satisfactory to differentiate all types of cells simultaneously.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Cytological and Cytochemical Investigations of the Adenohypophysis of the Sheep

Mikami

Daimon

1968

Arch. Histol. Jap., Arch. Histol. Jpn

View full text Add to dashboard Cite

Section: Histochemical Observationmentioning

confidence: 66%

Section: Histochemical Observationmentioning

confidence: 99%

See 1 more Smart Citation

Cytological and Cytochemical Investigations of the Adenohypophysis of the Sheep

Mikami

Daimon

1968

Arch. Histol. Jap., Arch. Histol. Jpn

View full text Add to dashboard Cite

“…They further found a stimulated picture of the cells of thyroid follicles in chronic phases. Since their observation was reconfirmed by Ishikawa and Totsuka (1968) Paget and Eccleston (1960).…”

mentioning

confidence: 89%

Identification of the Thyrotrophs with the Gonadotrophs in the Anterior Pituitaries of Thyroidectomized Rats

Yoshimura

Ishikawa

1969

Endocrinol Japon

View full text Add to dashboard Cite

“…Serial sections of 6 microns thick were obtained using a rotatory microtome. The deparaffused sections were stained routinely for chromatophilic substance using thionin method of Paget & Eccleston (1960) procedures. The sections were then rinse in distilled water, dehydrated through ascending grades of alcohol, cleared in xylene and mounted in DPX for chromatophilic substance observation.…”

Section: Methodsmentioning

confidence: 99%

Effects of Chronic Administration of Efavirenz on the Chromatophilic Substance of the Intracranial Auditory Relay Centres of Adult Wistar Rats

Adjene

Igbigbi

2012

Int. J. Morphol.

View full text Add to dashboard Cite

SUMMARY:The effects of chronic administration of efavirenz commonly used as part of highly active antiretroviral therapy (HAART) for the treatment of Human Immunodeficiency Virus (HIV) type-1 therapy on the chromatophilic substance of the intracranial auditory relay centre namely the inferior colliculus and medial geniculate body of adult wistar rats were carefully studied. The rats of both sexes (n=20), with an average weight of 200g were randomly assigned into treatment (n=10) and control (n=10) groups. The rats in the treatment group received 600 mg/70kg body weight of efavirenz dissolved in distilled water daily for 30 days through the orogastric tube. The control group received equal volume of distilled water daily for 30 days through the same route. The rats were fed with grower's mash obtained from Edo Feeds and Flour Mill Limited, Ewu, Edo state, Nigeria and given water liberally. The rats were sacrificed by cervical dislocation method on the thirty-first day of the experiment. The inferior colliculus and medial geniculate body were carefully dissected out and quickly fixed in 10% formal saline for histological study. The histological findings indicated that the treated sections of the inferior colliculus and medial geniculate body showed that the chromatophilics substances were less intensely stained as compared to the control. The parenchyme was vacuolated and with evidence of hypertrophy and more spaces between the axonal mesh around the sparsely distributed neurons as compared to the control group. The treated section of the inferior colliculus showed neurons with faintly stained chromatophilics substances in large, medium and small sized neurons while that of the medial geniculate body showed less intense and enlarge chromatophilics substances with some vacuolations. Chronic administration of efavirenz may therefore have an adverse effect on the chromatophilics substances of the inferior colliculus and medial geniculate body of adult wistar rats. It is recommended that further studies aimed at corroborating these observations be carried out.

show abstract

Simultaneous Specific Demonstration of Thyrotroph, Gonadotroph and Acidophil Cells in the Anterior Hypophysis

Cited by 35 publications

References 5 publications

Cytological and Cytochemical Investigations of the Adenohypophysis of the Sheep

Cytological and Cytochemical Investigations of the Adenohypophysis of the Sheep

Identification of the Thyrotrophs with the Gonadotrophs in the Anterior Pituitaries of Thyroidectomized Rats

Effects of Chronic Administration of Efavirenz on the Chromatophilic Substance of the Intracranial Auditory Relay Centres of Adult Wistar Rats

Contact Info

Product

Resources

About