Simultaneous quantitation and identification of intact Nandrolone phase II oxo‐metabolites based on derivatization and inject LC–MS/(HRMS) methodology
Panagiotis Sakellariou,
Polyxeni Kiousi,
Michael Petrou
et al.
Abstract:AbstractΑ sensitive and selective derivatization and inject method for the quantification of intact nandrolone phase II oxo‐metabolites was developed and validated using liquid chromatography ‐ (tandem high resolution) mass spectrometry (LC–MS/(HRMS)). For the derivatization, Girard's reagent T (GRT) was used directly in natural urine samples and the analysis of the metabolites of interest was performed by direct injection into LC–MS/(HRMS) system operating in positive ionization mode. Derivatization enabled t… Show more
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