Simultaneous Palatal Pleomorphic Adenoma and Mandibular Keratocystic Odontogenic Tumor in a Pediatric Patient

Abstract

Pleomorphic adenoma is the most common benign neoplasm of salivary glands. Their common location is in parotid gland, however, a lower percentage of these tumors might occur in minor glands. The epidemiology of this tumor shows that adults are the most affected, with rare occurrence in children or adolescents. We present the case report of pleomorphic adenoma located on the palate of a 10 year old. Excisional biopsy of the lesion followed by histopathologic examination of the biopsy specimen revealed ductal structures surrounded by plasmacytoid mioepithelial cells within a myxoid stroma, the final diagnosis corresponded to Pleomorphic Adenoma. Early detection and excision of this lesion in children are important to minimize potential recurrences or malignant transformation.

Pleomorphic Adenoma in a Young Female: Case Report

“…The age range was 5 to 19 years-old, with a mean age of 12.4 years-old. The incidence is higher in the second decade, with 25.7% of the tumors occurring in patients younger than 10 years (Byars et al, 1957;Crawford & Guernsey, 1967;Galich, 1969;Buehrle & Friedberg, 1972;Budnick, 1982;McIlveen et al, 1987;Lack & Upton, 1988;Fonseca et al, 1991;Austin & Crockett, 1992;Noghreyan et al, 1995;Lopez-Cedrún et al, 1996;de Courten et al, 1996;Chen et al, 1998;Shaaban et al, 2001;Jorge et al;Daniels et al, 2007;Dhanuthai et al, 2009;Arcuri et al, 2011;Ritwik & Brannon, 2012;Thangaswamy et al, 2012;Bovino et al, Table I. List of reported cases of Pleomorphic Adenoma in children and adolescents.…”

Multiple benign tumours in the oral and maxillofacial region of an adolescent

“…The occurrence of a salivary gland tumour with other oral tumours, such as this case, even in adults, is very rare. One other paediatric case has been reported a palatal pleomorphic adenoma with mandibular keratocystic odotogenic tumour in an 11‐year‐old boy.…”

Multidisciplinary Management of Benign Jaw Tumors in Children

“…However, a tooth is generally not missing and, therefore, they are believed to originate from additional remnants of the lamina not involved in tooth formation. Alternatively, in some cases they may arise from the oral mucosa, particularly in the retromolar region, because daughter cysts are found between the oral mucosa and the cyst in the retromolar region [44].…”