Simultaneous onset of COVID‐19 and autoimmune haemolytic anaemia

Covid-19 associated autoimmune thrombotic thrombocytopenic purpura: Report of a case

“…Autoimmune disorders including Guillain-Barré and APS have been described in the course of Covid-19 infection [4,5]. OIHA and ITP associated with Covid-19 have also been reported [6][7][8]. Common conditions associated with secondary TTP including lymphoproliferative disorders, other autoimmune disorders and collagen vascular diseases were excluded in our patient, which suggests that acquired TTP was driven by Covid-19 infection.…”

“…While the majority of patients have mild symptoms without pneumonia or mild pneumonia, the clinical spectrum of symptomatic Covid-19 cases ranges from mild to critically ill [3]. As previously reported, patients with Covid-19 may show a range of immune complications, such as autoimmune hemolytic anemia (OIHA), immune thrombocytopenia (ITP), Guillain-Barré and antiphospholipid syndrome (APS) [4][5][6][7][8]. Here we present a confirmed case of Covid-19 presenting with autoimmune thrombotic thrombocytopenic purpura (TTP).…”

Autoimmune haemolytic anaemia and a marked rise in the lymphocyte count associated with COVID‐19 in a patient with treatment‐naïve chronic lymphocytic leukaemia: a case report

“…AIHA has been reported with COVID‐19 9–11 , and is well recognised with CLL 4 . The dysregulated immune response seen with COVID‐19 encompass a pro‐inflammatory T cell profile with an increase of Th17 and high cytotoxicity of CD8 + T cells, which is strongly associated with autoimmunity, as well as a pro‐inflammatory cytokine storm occurring in severe infection at about D 14 2 .…”

COVID‐19 insights from transfusion medicine

“…In rapid reporting succession, patients with COVID‐19 have been documented to develop cold agglutinin disease, 11 the relatively more common autoimmune haemolytic anaemia 12,13 or immune thrombocytopenia 14 and their combination as Evans syndrome 15 . Each of these clinical entities can progress to require transfusions of red cells or platelets.…”