Simultaneous measurement of methyl <i>tert</i>‐butyl ether and <i>tert</i>‐butyl alcohol in human serum by headspace solid‐phase microextraction gas chromatography–mass spectrometry

Zhang, Rui; Mei, Yong; Liu, Yanru; Dai, Hao; Xia, Hongfang; Zhang, Xin; Wu, Yukang; Gu, Yingying; Peng, Xiaowu

doi:10.1002/bmc.3448

Cited by 6 publications

(3 citation statements)

References 33 publications

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“…Ethers, particularly methyl tert‐butyl ether (MTBE), have been used as additives in gasoline for the last three decades [95]. Hence, due to its widespread usage led to increased exposure in human.…”

Section: Resultsmentioning

confidence: 99%

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Solid‐phase microextraction for the human biomonitoring of environmental chemicals: Current applications and future perspectives

Kim

Karthikraj

2020

J of Separation Science

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Sample preparation is one of the crucial steps in the analytical chemistry including human biomonitoring studies. Although there are several traditional approaches available, solid‐phase microextraction is emerged as one of the pioneering techniques due to its simplicity, rapidness, wide applicability, and miniaturization of traditional sample preparation (e.g., use of less or no organic solvents). There are few earlier review articles available on the advancements in solid‐phase microextraction and its use for the measurement of environmental chemicals in various types of environmental samples. However, a collective information on applicability and current usage of solid‐phase microextraction for the human biomonitoring of environmental chemicals are scarce, nonetheless, rising demands on innovative analytical approaches for human biomonitoring studies. Hence, in this review article, we covered the application of solid‐phase microextraction as extraction/purification methods for more than 15 classes of environmental chemicals to assess their respective exposure levels and associated health outcomes in various human population reported across the globe. Further, a detailed discussion on various types of matrix used, nature of coupled analytical instrumentations, and limitations and future perspectives of solid‐phase microextraction for human biomonitoring studies is presented in this review.

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Section: Resultsmentioning

confidence: 99%

“…Zhang et al. developed HS‐SPME coupled with GC‐MS technique for the simultaneous measurement of MTBE and its metabolite tert‐butyl alcohol in human serum [95]. A high concentration of MTBE was found in gas station workers (median: 6.04 μg/L) compare to the controls (median: 0.22 μg/L) (Table 2).…”

Section: Resultsmentioning

confidence: 99%

Solid‐phase microextraction for the human biomonitoring of environmental chemicals: Current applications and future perspectives

Kim

Karthikraj

2020

J of Separation Science

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“…For further demonstrating the superiority of the developed HS-SPME-GC-FID method with PPy@MIL-101(Cr) nanosorbent, its analytical performances were compared with some similar procedures that are reported in the literature [25][26][27][28][29][30][31][32]. The results are summarized in Table 1.…”

Section: Analytical Performancesmentioning

confidence: 99%

Chromium-Based Polypyrrole/MIL-101 Nanocomposite as an Effective Sorbent for Headspace Microextraction of Methyl tert-Butyl Ether in Soil Samples

Darabi

Ghiasvand

2020

Molecules

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The performance of headspace solid-phase microextraction (HS-SPME) was upgraded by easy and low-cost preparation of a new nanocomposite fiber. A polypyrrole/chromium-based metal–organic framework, PPy@MIL-101(Cr), nanocomposite was electrochemically synthesized and simultaneously coated on a steel wire as a microextraction sorbent. The morphology and chemical structure of the prepared nanocomposite was characterized by Fourier-transform infrared spectrometry (FT-IR), scanning electron microscopy (SEM), and energy dispersive X-ray analysis (EDX) techniques. The microsorbent was used for sampling of methyl-tert-butyl ether (MTBE) in solid samples, through an HS-SPME sampling strategy, followed by GC-FID measurement. The optimal experimental conditions, including extraction temperature, extraction time, and GC desorption conditions, were evaluated and optimized. The proposed procedure showed good sensitivity (limit of detection was 0.01 ng·g−1) and precision (relative standard deviation was 8.4% for six replicated analyses). The calibration curve was linear over the range of 5–40,000 ng·g−1, with a correlation coefficient of 0.994. The limit of quantification was 0.4 ng·g−1. The fabricated fiber exhibited good repeatability and reproducibility for the sampling of MTBE, with average recovery values of 88–114%. The intra-fiber and inter-fiber precisions were found to be 8.4% and 19%, respectively. The results demonstrated the superiority of the PPy@MIL-101(Cr)-coated fiber in comparison with handmade (polypyrrole, PPY) and commercial fibers (polyacrylate, PA; polydimethylsiloxane, PDMS; and divinylbenzene/carboxen/polydimethylsiloxane, DVB/CAR/PDMS) for the analysis of solid samples. The developed method was successfully employed for the analysis of MTBE in different soil samples contaminated by oil products.

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Urinary biomonitoring of fuel ether oxygenates using a needle trap device packed with a novel molecularly imprinted polymer surface modified Zeolite Y

Jalili,

Ghiasvand,

Ebrahimzadeh

et al. 2024

Journal of Chromatography A

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Simultaneous measurement of methyl tert‐butyl ether and tert‐butyl alcohol in human serum by headspace solid‐phase microextraction gas chromatography–mass spectrometry

Cited by 6 publications

References 33 publications

Solid‐phase microextraction for the human biomonitoring of environmental chemicals: Current applications and future perspectives

Solid‐phase microextraction for the human biomonitoring of environmental chemicals: Current applications and future perspectives

Chromium-Based Polypyrrole/MIL-101 Nanocomposite as an Effective Sorbent for Headspace Microextraction of Methyl tert-Butyl Ether in Soil Samples

Urinary biomonitoring of fuel ether oxygenates using a needle trap device packed with a novel molecularly imprinted polymer surface modified Zeolite Y

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