Simultaneous estimation of tongue volume and fat fraction using IDEAL‐FSE

Abstract

Purpose: To determine whether high-resolution, high signal-to-noise ratio (SNR) images of the tongue acquired with IDEAL-FSE (iterative decomposition of water and fat with echo asymmetry and least squares estimation) will provide comparable volumetric measures to conventional nonfatsuppressed FSE imaging and to determine the feasibility of estimating the proportion of lingual fat in adults using IDEAL-FSE imaging. Materials and Methods:Healthy volunteers underwent magnetic resonance imaging of the tongue using both IDEAL-FSE and conventional FSE sequences. The tongue was manually outlined to derive both volumetric and fat fraction measures. Intraclass correlation coefficients (ICCs) were computed for intrarater measurement reliability and Spearman's rank correlation tested the relationship between IDEAL-FSE and conventional volumetric measures of the tongue. ; r ϭ 0.988, P Յ 0.01). The average fat signal fraction across participants was 26.5%. Intrarater reliability was excellent for all measures (ICC Ն 0.92). Conclusion:Our results indicate that IDEAL-FSE provided similar lingual volume estimates to conventional FSE imaging obtained in both the current and previous studies. IDEAL-FSE measures of lingual fat composition may be useful in studies that aim to increase lingual muscle strength and volume in swallowing and speech-disordered populations.

Bulbar muscle weakness and fatty lingual infiltration in glycogen storage disorder type IIIa

“…Quantitative fat-fraction MRI of skeletal muscle already shows promise in other neuromuscular disorders, including Duchene muscular dystrophy and Charcot-Marie-Tooth [18][19][20]. However, true quantitative MR assessment of lingual fat in patients with neuromuscular disorders, including GSD II and GSD III, has not yet been reported to our knowledge, though quantitative fat-fraction imaging of the normal tongue has been performed [21]. Fat fraction quantitative MRI may provide a more robust and reproducible measure of abnormal fatty involvement of the tongue in comparison to previously employed qualitative techniques and allow for more powerful statistical analyses to be performed when employed as an outcome measure in clinical trials.…”

Effects of Inhaled Fluticasone on Upper Airway during Sleep and Wakefulness in Asthma: A Pilot Study

“…High-resolution anatomic images progressing from the roof of the hard palate to the tip of the epiglottis 26 were acquired using the Iterative Decomposition of water and fat with echo asymmetry and least squares estimation fast spin-echo (IDEAL-FSE) method, 27 to allow in vivo determination of total fat volume and fat fraction in the structures surrounding the pharyngeal UAW (see supplemental material for details). Scans were obtained on 3 participants.…”

Efeitos da terapia miofuncional orofacial em pacientes com ronco primário e apneia obstrutiva do sono na anatomia e função da via aérea

“…[30] Recentemente novos métodos que mensuram a quantidade de gordura, separando gordura e água, foram utilizados mensurando a gordura na língua. [38] Além disso, a RM tem sido utilizada para mensurar modificações na VAS de pacientes com AOS, de acordo com os tratamentos como: perda de peso, [34] no uso de placa de avanço mandibular, [35] uso de novo dispositivo que gera pressão negativa intra-oral [39] e cirurgia na VAS, [40] demonstrando as modificações anatômicas.…”