Simultaneous estimation of epigallocatechin, fisetin, and quercetin in  Acacia suma and its potential against postprandial hyperglycemia

Kanbarkar, Nikita; Mishra, Shashank Shekhar; Dodmani, Sunil; Kurangi, Bhaskar

doi:10.47552/ijam.v13i1.2361

Cited by 4 publications

(1 citation statement)

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“…The ethanol injection technique was used to prepare Vinpocetine-loaded niosomes (VLN). Briefly, several ratios of cholesterol, span-60, and Vinpocetine (10mg) were precisely weighed and dissolved in 10ml of ethanol utilizing bath sonication at 60 o C. The transparent organic solution was immediately transferred into the aqueous solution at 60°C while the mixture was vigorously stirred at 500 rpm on a magnetic stirrer (Remi) using a teflon coated bead (24,25). The aqueous solution rapidly changed into milky solution suggested niosomes formation.…”

Section: Preparation Of Vinpocetine Loaded Niosomes (Vln)mentioning

confidence: 99%

Development and Validation of UV-Spectrophotometric Method for Estimation of Vinpocetine in Marketed Formulation and Nanoformulation

Kumar HB,

Kurangi,

Soudagar

et al. 2023

IJAM

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A quick, accurate, and cost-effective UV spectroscopy method was developed to estimate the Vinpocetine concentration in bulk, tablet dosage formulations and niosomes formulations, using a solvent ratio of (6:4) methanol: water. According to ICH guidelines, the proposed technique was validated and developed. In spite of linearity, precision, accuracy, specificity, LOD, and LOQ, like parameters were validated by using UV/visible spectroscopy technique to analyze a spiked Vinpocetine solution. The wavelength at which the drug's maximum absorbance peak was obtained at 274 nm and the solvents used as methanol: water (6:4 w/v). The ethanol injection technique was used to prepare niosomes to analyze Vinpocetine in UV / visible spectrophotometric method.During the inter and intra-day studies, it was discovered that the developed UV technique was accurate, with % relative standard deviation ranging from 0.27 to 0.46 and 0.26 to 0.46, respectively. Vinpocetine overall recovery percentage was discovered to be between 98.42 to 99.82 %. LOQ and LOD were calculated to estimate the method's sensitivity, and they were observed to be 0.4565 µg/ml and 0.1506 µg/ml, respectively. The estimation of Vinpocetine content in bulk form, marketed formulations and niosomes was achieved using the developed methodology. : A quick, accurate, and economical UV spectrophotometric method has been developed. As a result, the suggested UV spectroscopic technique has been developed to estimate the vinpocetine concentration in bulk, tablet dosage formulations, and niosomes formulations.

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Section: Preparation Of Vinpocetine Loaded Niosomes (Vln)mentioning

confidence: 99%