Simultaneous determination of eleven estrogenic and odorous chloro- and bromo-phenolic compounds in surface water through an automated online headspace SPME followed by on-fiber derivatization coupled with GC-MS

Yuan, Shuai; Liu, Ze‐hua; Lian, Haixian; Yang, Chuang-tao; Lin, Qing; Yin, Hua; Dang, Zhi

doi:10.1039/c7ay00641a

Cited by 32 publications

(5 citation statements)

References 57 publications

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“…analysis needs a derivatization procedure for hydroxyl functional groups. The most commonly used derivatization reagents are TMS reagents containing N-methyl-N-(trimethylsilyl)trifluoroacetamide), N-methyl-N-tertbutyldimethylsilyl-trifluoroacetamide, BSTFA and TMCS for derivatization of polyphenolic compounds and their metabolites (25,28,34,35). TMS reagents are hydrolyzed in aqueous solutions.…”

Section: Resultsmentioning

confidence: 99%

Graphene Oxide-Ionic Liquid Used As Solid-Phase Microextraction Coating For Polyphenolic Compounds' Extraction And Determination With GC-MS After On-Fiber Derivatization In Wine

Tashakkori

Tağaç

Merdıvan

2020

Journal of the Turkish Chemical Society Section A: Chemistry

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We describe the use of a home-made fiber coated by graphene oxide modified by an ionic liquid having methylimidazolium cation with an amino-functional group for the extraction of polyphenolic compounds (P.C.s). We then performed the determination by gas chromatography coupled with mass spectrometry after on-fiber derivatization. The authors optimized the main parameters influencing the extraction and derivatization processes. The on-fiber derivatization was employed within 15 min at 60 º C using 20 µL of trimethylsilyl reagents. Under the optimized conditions, the calibration curves for 12 P.C.s were linear from 0.1 to 1000 µg/L, and the detection limits were between 0.02 and 0.1 µg/L. We determined the single fiber repeatability obtained for all calibration points and the fiber to fiber reproducibility for 100 µg/L to be < 14.82% and < 5.87%, respectively. The extraction efficacy of the home-made fiber due to high intermolecular and electrostatic attractions was much better than the commercial fibers. We successfully applied the method to the analysis of P.C.s in wine samples with the recoveries from 72.8 to 99.9%.

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Section: Resultsmentioning

confidence: 99%

Graphene Oxide-Ionic Liquid Used As Solid-Phase Microextraction Coating For Polyphenolic Compounds' Extraction And Determination With GC-MS After On-Fiber Derivatization In Wine

Tashakkori

Tağaç

Merdıvan

2020

Journal of the Turkish Chemical Society Section A: Chemistry

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“…For the convenience of comparison, relative activity is used, and the maximal enzyme activity is arbitrarily set to 100%. The limit of detection (LOD) of the spectrophotometric method was calculated according to three times of the standard deviation, which was obtained from nine repeated determinations of the lowest p NP concentration used for the standard calibration curve. , The LOD of this method for p NP was 0.22 μM, which is equal to 0.22 U/L for arylsulfatase and β-glucuronidase.…”

Section: Methodsmentioning

confidence: 99%

Inhibition Properties of Arylsulfatase and β-Glucuronidase by Hydrogen Peroxide, Hypochlorite, and Peracetic Acid

et al. 2021

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Arylsulfatase and β-glucuronidase are two important enzymes in humans, which play an important role in the dynamic equilibrium of steroidal estrogens. This work probably for the first time reported that hydrogen peroxide (H2O2), hypochlorite, and peracetic acid (PAA) could effectively inhibit the activities of arylsulfatase and/or β-glucuronidase. The 50% of inhibitions (IC50) of H2O2, hypochlorite, and PAA on arylsulfatase were found to be 142.90 ± 9.00, 91.83 ± 10.01, and 43.46 ± 2.92 μM, respectively. The corresponding IC50 values of hypochlorite and PAA on β-glucuronidase were 704.90 ± 41.40 and 23.26 ± 0.82 μM, whereas H2O2 showed no inhibition on β-glucuronidase. The inhibitions of arylsulfatase and/or β-glucuronidase by these three chemicals were pH-dependent. It was further revealed that the inhibitions of hypochlorite on both arylsulfatase and β-glucuronidase were irreversible. On the contrary, the inhibitions by H2O2 and PAA were reversible. In addition, the inhibition by H2O2 was competitive and that by PAA was noncompetitive. In general, H2O2 and hypochlorite can be endogenously produced in humans, which suggested that the two compounds are potential endocrine disruption compounds (EDCs) as they can cause endocrine disruption via the inhibition of arylsulfatase and β-glucuronidase. This work further indicated that any agent that can induce the production of H2O2 or hypochlorite in humans is a potential EDC, which explains why some EDCs with very weak or no estrogenic potency can cause endocrine disruption, which is confirmed in epidemiological studies.

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“…The determination of chlorophenols in water is very important due to its high toxicity level ( Gallego et al, 2018 ). Many studies had reported the extraction of chlorophenols and some estrogenic compounds using HS-SPME, followed by on-fiber derivatization coupled with GC-MS ( Yuan et al, 2017 ).…”

Section: Applicationsmentioning

confidence: 99%

Solventless Microextration Techniques for Pharmaceutical Analysis: The Greener Solution

Mohamed

2022

Front. Chem.

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Extensive efforts have been made in the last decades to simplify the holistic sample preparation process. The idea of maximizing the extraction efficiency along with the reduction of extraction time, minimization/elimination of hazardous solvents, and miniaturization of the extraction device, eliminating sample pre- and posttreatment steps and reducing the sample volume requirement is always the goal for an analyst as it ensures the method’s congruency with the green analytical chemistry (GAC) principles and steps toward sustainability. In this context, the microextraction techniques such as solid-phase microextraction (SPME), stir bar sorptive extraction (SBSE), microextraction by packed sorbent (MEPS), fabric phase sorptive extraction (FPSE), in-tube extraction dynamic headspace (ITEX-DHS), and PAL SPME Arrow are being very active areas of research. To help transition into wider applications, the new solventless microextraction techniques have to be commercialized, automated, and validated, and their operating principles to be anchored to theory. In this work, the benefits and drawbacks of the advanced microextraction techniques will be discussed and compared, together with their applicability to the analysis of pharmaceuticals in different matrices.

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Simultaneous determination of eleven estrogenic and odorous chloro- and bromo-phenolic compounds in surface water through an automated online headspace SPME followed by on-fiber derivatization coupled with GC-MS

Abstract: HS-SPME followed by on-fiber derivatization coupled with GC-MS is developed for simultaneous determination of eleven estrogenic chloro- and bromo-phenolic compounds.

Cited by 32 publications

References 57 publications

Graphene Oxide-Ionic Liquid Used As Solid-Phase Microextraction Coating For Polyphenolic Compounds' Extraction And Determination With GC-MS After On-Fiber Derivatization In Wine

Graphene Oxide-Ionic Liquid Used As Solid-Phase Microextraction Coating For Polyphenolic Compounds' Extraction And Determination With GC-MS After On-Fiber Derivatization In Wine

Inhibition Properties of Arylsulfatase and β-Glucuronidase by Hydrogen Peroxide, Hypochlorite, and Peracetic Acid

Solventless Microextration Techniques for Pharmaceutical Analysis: The Greener Solution

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