Simultaneous Determination of Clarithromycin, Tinidazole and Omeprazole in Helicure Tablets Using Reflectance Near-Infrared Spectroscopy with the Aid of Chemometry

Salam, Hadad GM Abdel

doi:10.4172/2153-2435.1000354

Cited by 3 publications

(2 citation statements)

References 42 publications

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“…Moreover, it is highly uncommon to use only a single preprocessing technique, due to each preprocessing technique providing complementary information. In Xu et al [52], some combinations of preprocessing techniques were proposed to improve the stability of the models, which has been recently backed by other studies [53][54][55][56]. In this work, nine combinations of different techniques have been considered to preprocess the inputs.…”

Section: Data Preprocessingmentioning

confidence: 99%

Detection of Bovine Mastitis in Raw Milk, Using a Low-Cost NIR Spectrometer and k-NN Algorithm

et al. 2021

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Among the bovine diseases, mastitis causes high economic losses in the dairy production system. Nowadays, detection under field conditions is mainly performed by the California Mastitis Test, which is considered the de facto standard. However, this method presents with problems of slowness and the expensiveness of the chemical-reactive process, which is deeply dependent on an expert’s trained eye and, consequently, is highly imprecise. The aim of this work is to propose a new method for bovine mastitis detection under field conditions. The proposed method uses a low-cost, smartphone-connected NIR spectrometer which solves the aforementioned problems of slowness, expert dependency and disposability of the chemical methods. This method uses spectra in combination with two k-Nearest Neighbors models. The first model is used to detect the presence of mastitis while the second model classifies the positive cases into weak and strong. The resulting method was validated by using a leave-one-out technique where the ground truth was obtained by the California Mastitis Test. The detection model achieved an accuracy of 92.4%, while the one classifying the severity showed an accuracy of 95%.

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Section: Data Preprocessingmentioning

confidence: 99%

Detection of Bovine Mastitis in Raw Milk, Using a Low-Cost NIR Spectrometer and k-NN Algorithm

et al. 2021

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“…Many methods have been developed and applied in the detection of TDZ like electrochemical techniques [6–10], titrimetric [11], spectrophotometry [11–17], and HPLC [12, 16, 18–22]. …”

Section: Introductionmentioning

confidence: 99%

Electrochemical Behaviour of Tinidazole at 1,4-Benzoquinone Modified Carbon Paste Electrode and Its Direct Determination in Pharmaceutical Tablets and Urine by Differential Pulse Voltammetry

Nikodimos

Hagos

2017

Journal of Analytical Methods in Chemistry

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A simple and highly sensitive electrochemical method based on a 1,4-benzoquinone modified carbon paste electrode (1,4-BQMCPE) was described for the determination of tinidazole (TDZ). In Britton Robinson buffer solution, TDZ yields well-defined irreversible reduction peak at −0.344 V on a 1,4-BQMCPE. Compared with that on a bare CPE, the reduction peak of TDZ increased significantly on the modified CPE and the effects of different parameters on the voltammetric responses were also investigated. Differential pulse voltammetric method was proposed and optimized for TDZ determination and its reductive peak current response at 1,4-BQMCPE was found to show linear dependence on the concentration of TDZ in the range of 1.0 × 10−6 to 5.0 × 10−4 M with a linear regression equation, correlation coefficient, limit of detection (LOD), and limit of quantification (LOQ) of IPC (μA) = 0.19958 + 0.02657C (μM), 0.99486, 1.10 × 10−7 M, and 3.77 × 10−7, respectively. Excellent recovery results for spiked TDZ in pharmaceutical tablet samples ranging within 97.44–97.51% and in urine ranging within 95.37–96.91% were observed. The selectivity of the method for TDZ was further studied in the presence of selected potential interferents and confirmed the potential applicability of the developed method for the determination of TDZ.

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A review of pretreatment and analysis of macrolides in food (Update Since 2010)

Yuan

Zhou

et al. 2020

Journal of Chromatography A

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Simultaneous Determination of Clarithromycin, Tinidazole and Omeprazole in Helicure Tablets Using Reflectance Near-Infrared Spectroscopy with the Aid of Chemometry

Cited by 3 publications

References 42 publications

Detection of Bovine Mastitis in Raw Milk, Using a Low-Cost NIR Spectrometer and k-NN Algorithm

Detection of Bovine Mastitis in Raw Milk, Using a Low-Cost NIR Spectrometer and k-NN Algorithm

Electrochemical Behaviour of Tinidazole at 1,4-Benzoquinone Modified Carbon Paste Electrode and Its Direct Determination in Pharmaceutical Tablets and Urine by Differential Pulse Voltammetry

A review of pretreatment and analysis of macrolides in food (Update Since 2010)

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