Simultaneous determination of BTEX and their metabolites using solid-phase microextraction followed by HPLC or GC/MS: An application in teeth as environmental biomarkers

Lifestyle and occupational factors affecting exposure to BTEX in municipal solid waste composting facility workers

“…Extraction of BTEX compounds from urine was carried out using Headspace Solid-Phase Micro-extraction (HS-SPME) in glass headspace vials (20 mL, Gerstel, Germany) crimped with 1.3 mm butyl/PTFE septa, containing stirring bars. The apparatus and procedures used in this study have been described in our previous studies (González et al, 2017;Rafiee et al, 2018a). Briefly, a gas chromatography (GC, Agilent 7890N, Agilent Co) was used to analyze urinary BTEX.…”

A review of new adsorbents for separation of BTEX biomarkers

“…Measurement of VOCs by the SPME method, which is excreted in urine as unmetabolized compounds, is one of the essential tools for evaluating people exposed to pollutants in environmental and occupational exposures. The use of headspace–solid‐phase microextraction (HS–SPME) has increased recently for extracting volatile and semi‐volatile compounds from standard matrices such as urine, serum and exhaled air (Aranda‐Rodriguez et al, 2015; Johannes L González et al, 2017; Gottzein et al, 2010; Hamidi et al, 2018; J.‐E. Lee et al, 2019; Poormohammadi et al, 2017; Sakhvidi et al, 2012; Zhang et al, 2015).…”

“…Several early studies used commercial fibers to analyze VOCs in urine samples and performed analysis with a GC system (Johannes L González et al, 2017; Gottzein et al, 2010; Kataoka & Saito, 2011; J.‐E. Lee et al, 2019).…”

“…Studies on the use of new adsorbents to analyze biomarkers of BTEX compounds in blood and human teeth are few. However, in one study, BTEX compounds were analyzed in human teeth using the SPME method (González et al, 2017). In another study, BTEX compounds in blood, urine and exhaled air were determined based on pharmacological models (Marchand et al, 2015).…”

Lipidomics Profiling of HepG2 Cells and Interference by Mycotoxins Based on UPLC-TOF-IMS

“…There is no doubt that hyphenated and multidimensional techniques based on mass spectrometry are currently the most extensive and effective tools for lipid/metabolite profiling and quantification. − For example, gas chromatography–mass spectrometry shows excellent resolution ability in fatty acid analysis , and liquid chromatography is often coupled online with ion trap, triple-stage quadrupole, Q-Exactive Orbitrap mass spectrometry, etc. , Nevertheless, these techniques are limited by factors including matrix effects and interference of isomers and isobars created by the structural diversity of metabolites and lipids, which can confound identification. Newer innovations, such as IMS, are gaining popularity for the analysis of lipids, where large numbers of ions have the same mass values arising from different headgroups, different connectivities of fatty acyls, and different locations of double bonds within the fatty acyls. , Reduced mobilities and collision cross sections (CCSs), which are determined for lipid identification by comparison with lipid databases, are more reproducible than the retention time (RT) due to the potential for RT shifts and have been used to determine the degree of isomerism (e.g., different double bond positions, geometries) in untargeted lipidomics .…”