Simultaneous determination of aminoglycoside antibiotics in feeds using high performance liquid chromatography with evaporative light scattering detection

Abstract

A HPLC-ELSD method was developed for the simultaneous detection of ten aminoglycoside antibiotics.

Antibiotic use in chicken farms in northwestern China

“…Recently, however, the Ministry of Agriculture approved 21 antibiotic products that may be added as growth promoters in commercial feeds [8]. Previous studies reported high concentrations of several antibiotics in animal commercial feeds in China [12,32]. Our study found that all farmers used commercial feeds on their farms.…”

Chemiluminescence imaging immunoassay for multiple aminoglycoside antibiotics in cow milk

“…According to the regulation of European Union (European Commission 2010), the maximum residue limits (MRL) for kanamycin (KAN) and streptomycin/dihydrostreptomycin (STR/diSTR) in cow milk are 150 and 200 ng mL À1 , respectively. Besides conventional chromatography methods (Preu et al, 1998;Oertel et al, 2004;Kaufmann & Maden, 2005;Liu et al, 2017), immunoassays have been applied to screen the antibiotics in animal-origin food due to be sensitive, rapid and easy-operated (Verheijen et al, 2000;Abuknesha & Luk, 2005;He et al, 2016;. Besides detecting one target specifically by immunoassay (Gu et al, 2016;Kong et al, 2017), another demand to develop the multiplex assays for more targets is growing concern because of its benefits, such as enhancing sample throughput, shorting assay time and decreasing sample consumption and cost (Zhang et al, 2004).…”

Simultaneous determination of ten aminoglycoside antibiotics in aquatic feeds by high‐performance liquid chromatography quadrupole‐orbitrap mass spectrometry with pass‐through cleanup

“…Aminoglycosides (AGs) are broad‐spectrum antibiotics, which are particularly active against both gram‐positive and gram‐negative bacteria . In aquaculture, AGs have been widely used as veterinary drugs to treat bacterial infectious diseases .…”

“…Aminoglycosides (AGs) are broad-spectrum antibiotics, which are particularly active against both gram-positive and gram-negative bacteria. 1 In aquaculture, AGs have been widely used as veterinary drugs to treat bacterial infectious diseases. 2 In recent years, AGs have also been employed as a feed additive to promote growth and increase feed efficiency, because it can facilitate absorption of nutrition in animals.…”