Simultaneous determination of acesulfame-K, aspartame and stevioside in sweetener blends by ultraviolet spectroscopy with variable selection by sipls algorithm

Abstract

A chemometric-assisted UV absorption spectroscopic method is proposed for the simultaneous determination of acesulfame-K, aspartame and stevioside in raw powder mixtures of commercial sweeteners. The synergy interval partial least squares (siPLS) algorithm was applied to select the optimum spectral range and their combinations. The utilization of spectral region selection aims to construct better partial least squares (PLS) model than that established from the full-spectrum range. The results show that the siPLS algorithm can find out an optimized combination of spectral regions, yielding lower relative standard error of prediction (RSEP) and root mean square error of prediction (RMSEP), as well as simplifying the model. The RMSEP and RSEP obtained after selection of intervals by siPLS were 0.1330 μg·ml–1 and 1.50 % for acesulfame-K, 0.2540 μg·ml–1 and 1.64 % for aspartame, 1.4041 μg·ml–1 and 2.03 % for stevioside respectively. The recovery values range from 98.12 % to 101.88 % for acesulfame-K, 98.63 % to 102.96% for aspartame, and 96.38 % to 104.04 % for stevioside respectively.

Efficient processing of Single and Multiple Spectral Variables for Resolution and Quantitation of Paracetamol, Chlorzoxazone and Diclofenac

“…The main principle of this method is to develop PLS regression model in smaller selected spectral wavelength region using the same or less number of latent variables. Many algorithms have been proposed for the selection of characteristic wavelength, However, among the different types of utilization algorithms, the iPLS method has gained much attention due to its high efficiency and ability to represent results in a graphical manner, focusing on models with specified intervals and interpretation 32 . In recent years, many successful applications of iPLS based methods have been reported in the literature 45 ,46…”

“…So, the aim of this work is primarily to simultaneously determine the three components in bulk powder and tablet dosage form without prior separation or pre-treatment derivativezation which considered a great benefit in quality control laboratories and to compare the efficiency of single and multiple variables regression methods for such resolution and quantitation. Thus, spectral resolution and quantitation of the selected components was achieved using single variable continuous wavelet transform (CWT) and Savitsky-Golay derivatization (SAVGOL) methods and multiple variables synergy interval partial least squares (siPLS) 32 , and normal partial least squares (PLS) methods.…”

A pilot-scale investigation of ozonation and advanced oxidation processes at Choa Chu Kang Waterworks

“…During the pilot testing, the selected compounds were mixed in cocktail solution and spiked into water at the same time. Grabbed water samples were analyzed at the PUB laboratories (Zhang et al 2006;Hu et al 2008;Wu et al 2008;He et al 2012).…”

Simultaneous voltammetric determination of aspartame and acesulfame-K in food products using an anodically pretreated boron-doped diamond electrode

“…Several methods for the individual or simultaneous determination of articial sweeteners have been developed using different techniques, such as liquid chromatography, hyphenated or not with mass spectrometry, [8][9][10][11][12] capillary electrophoresis, 13 and spectrophotometry. 14,15 However, in comparison to electroanalytical methods, those methods are oen based on more expensive instruments and commonly involve complicated and lengthy procedures. Electroanalytical techniques, such as the voltammetric ones (e.g.…”