Simultaneous detection of salivary Δ9-tetrahydrocannabinol and alcohol using a Wearable Electrochemical Ring Sensor

Mishra, Rupesh K.; Sempionatto, Juliane R.; Li, Zhanhong; Brown, Christopher M.; Galdino, Nathália Magno; Shah, Rushabh; Liu, Shuyang; Hubble, Lee J.; Bagot, Kara; Tapert, Susan F.; Wang, Joseph

doi:10.1016/j.talanta.2020.120757

Cited by 106 publications

(70 citation statements)

References 42 publications

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“…Virtual delivery of CM using remote verification of substance use is under evaluation as a remotely delivered treatment for alcohol use ( NCT03883126 ), with promising preliminary findings ( Koffarnus, Kablinger, Swallow, & Bickel, 2015 ). Abstinence verification technologies for alcohol use include remote breath sensors ( Keays, 2014 ; Ofir, Navon, Yichie, & Biron, 2014 ) and wearables ( Fairbairn & Kang, 2019 ; Flango & Cheesman, 2009 ); and development is underway for wearables and remote sensors to detect cocaine ( Holtyn et al, 2019 ), nicotine ( Imtiaz, Ramos-Garcia, Wattal, Tiffany, & Sazonov, 2019 ; Tai et al, 2020 ), cannabis ( Mishra et al, 2020 ), and simultaneous use of multiple substances ( Xue et al, 2020 ). Research is necessary to: 1) support deploying CM into virtual care, including evaluating the feasibility and effectiveness of remotely delivered CM for a variety of SUDs, and 2) develop implementation strategies to embed remote CM into existing clinics sustainably.…”

Section: Behavioral Economic Interventions Are Well-suited For Virtuamentioning

confidence: 99%

Considerations for remote delivery of behavioral economic interventions for substance use disorder during COVID-19 and beyond

Coughlin

Bonar

Bickel

2021

Journal of Substance Abuse Treatment

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The response to the COVID-19 crisis has created direct pressure on health care providers to deliver virtual care, and has created the opportunity to develop innovations in remote treatment for people with substance use disorders. Remote treatments provide an intervention delivery framework that capitalizes on technological innovations in remote monitoring of behaviors and can efficiently use information collected from people and their environment to provide personalized treatments as needed. Interventions informed by behavioral economic theories can help to harness the largely untapped potential of virtual care in substance use treatment. Behavioral economic treatments, such as contingency management, the substance-free activity session, and episodic future thinking, are positioned to leverage remote monitoring of substance use and to use personalized medicine frameworks to deliver remote interventions in the COVID-19 era and beyond.

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Section: Behavioral Economic Interventions Are Well-suited For Virtuamentioning

confidence: 99%

Considerations for remote delivery of behavioral economic interventions for substance use disorder during COVID-19 and beyond

Coughlin

Bonar

Bickel

2021

Journal of Substance Abuse Treatment

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“…A novel sensor ring concept, comprising a powerful wireless electronic board embedded into a ring platform and a readily replaceable printed dual-sensor electrode cap, was developed for the simultaneous, direct and rapid field detection of D9-tetrahydrocannabinol (THC) and alcohol in diluted saliva [ 86 ]. The ring sensing platform contained a voltammetric THC sensor based on a multi-walled carbon nanotubes MWCNTs/carbon electrode and an amperometric alcohol biosensor involving Prussian-blue (PB) mediator, coated with AOx/chitosan reagent layer on the ring cap ( Figure 11 b).…”

Section: Wearable Printed Electrodes For Biosensing Applicationsmentioning

confidence: 99%

“…SPEs fabricated on a temporary tattoo ( e ), bendable bandage ( f ), textile substrate ( g ), glove ( h ), water-soluble silk thin-film substrates (transferred to tooth enamel) ( i ), contact lens ( j ), or incorporated in a mouthguard ( k ), eyeglasess ( l ) or ring ( m ). Reprinted and adapted with permission of Springer [ 68 ] ( e , j , k ) Wiley [ 81 ] ( f ), Elsevier [ 82 ] ( a , g ), Elsevier [ 82 ]( b ), Wiley [ 83 ] ( c ), Wiley [ 65 ] ( h ), Nature Research [ 84 ] ( i ), Elsevier [ 85 ] ( l ), and Elsevier [ 86 ] ( c , m ).…”

Section: Figurementioning

confidence: 99%

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Screen-Printed Electrodes: Promising Paper and Wearable Transducers for (Bio)Sensing

2020

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Screen-printing technology has revolutionized many fields, including that of electrochemical biosensing. Due to their current relevance, this review, unlike other papers, discusses the relevant aspects of electrochemical biosensors manufactured using this technology in connection to both paper substrates and wearable formats. The main trends, advances, and opportunities provided by these types of devices, with particular attention to the environmental and biomedical fields, are addressed along with illustrative fundamentals and applications of selected representative approaches from the recent literature. The main challenges and future directions to tackle in this research area are also pointed out.

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“…There are wearable technologies that allow for biosensing of metabolites in sweat [ 74 , 75 ]; however, they have a long delay, some up to two hours, that makes them useless for on-site Driving While Intoxicated (DWI) analysis. Similar research has looked into saliva for the identification of tetrahydrocannabinol (THC) [ 76 ] and an overall approach that analyzes multiple types of legal and illegal compounds in sweat [ 77 ].…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in Noninvasive Biosensors for Forensics, Biometrics, and Cybersecurity

McGoldrick

Halámek

2020

Sensors

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Recently, biosensors have been used in an increasing number of different fields and disciplines due to their wide applicability, reproducibility, and selectivity. Three large disciplines in which this has become relevant has been the forensic, biometric, and cybersecurity fields. The call for novel noninvasive biosensors for these three applications has been a focus of research in these fields. Recent advances in these three areas has relied on the use of biosensors based on primarily colorimetric assays based on bioaffinity interactions utilizing enzymatic assays. In forensics, the use of different bodily fluids for metabolite analysis provides an alternative to the use of DNA to avoid the backlog that is currently the main issue with DNA analysis by providing worthwhile information about the originator. In biometrics, the use of sweat-based systems for user authentication has been developed as a proof-of-concept design utilizing the levels of different metabolites found in sweat. Lastly, biosensor assays have been developed as a proof-of-concept for combination with cybersecurity, primarily cryptography, for the encryption and protection of data and messages.

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Simultaneous detection of salivary Δ9-tetrahydrocannabinol and alcohol using a Wearable Electrochemical Ring Sensor

Cited by 106 publications

References 42 publications

Considerations for remote delivery of behavioral economic interventions for substance use disorder during COVID-19 and beyond

Considerations for remote delivery of behavioral economic interventions for substance use disorder during COVID-19 and beyond

Screen-Printed Electrodes: Promising Paper and Wearable Transducers for (Bio)Sensing

Recent Advances in Noninvasive Biosensors for Forensics, Biometrics, and Cybersecurity

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