Simultaneous colorimetric and electrochemical detection of trace mercury (Hg2+) using a portable and miniaturized aptasensor

Advances in colorimetric aptasensors for heavy metal ion detection utilizing nanomaterials: a comprehensive review

“…Similarly, Wu et al utilized this strategy to develop a colorimetric aptasensor for As 3+ and could detect As 3+ at a minimum concentration of 41 nM, 49 and Ulloa-Gomez et al used the induced aggregation effect of polystyrene on AuNPs to develop a colorimetric aptasensor with an LOD of 25 nM for Hg 2+ while maintaining high stability within 7 days. 50 In addition, the application of CTAB as a cationic surfactant in the development of a colorimetric aptasensor for As 3+ determination was also reported by Nguyen et al and Wu et al 51,52 Based on the work of Wu et al, Xu et al used PDDA to develop an aptasensor for Cd 2+ analysis and successfully applied it to the detection of rice with a detection range of 8.9-3560 nM and a LOD of 8.9 nM. 53 Importantly, they innovatively used the ColorAssist App in smartphones to quantify color observations.…”

Bottom‐up DNA nanostructure‐based paper as point‐of‐care diagnostic: From method to device

“…To avoid this issue, Ulloa-Gomez et al employed the specific aggregation of aptamer-functionalized polystyrene (PS)-AgNPs and PS-AuNPs particles for two types of detection of trace mercury (Hg 2þ ): colorimetric and electrochemical. 93 Lin et al used aptamers in a dualchannel design to capture fluorescence images and analyses the corresponding RGB (for red, green and blue) values using a smartphone, allowing simultaneous detection of two targets. 94 The expanding range of aptamers has led to the development of strategies for the detection of a wider range of targets.…”

“…To avoid this issue, Ulloa‐Gomez et al. employed the specific aggregation of aptamer‐functionalized polystyrene (PS)‐AgNPs and PS‐AuNPs particles for two types of detection of trace mercury (Hg 2+ ): colorimetric and electrochemical 93 . Lin et al.…”

Screening of a High-Affinity Aptamer for Aflatoxin M1 and Development of Its Colorimetric Aptasensor

“…Nucleic acid aptamers are a class of functional nucleic acids with specific recognition capabilities. , Due to their high recognition efficiency, good thermal stability, and easy modification and functionalization, nucleic acid aptamers are widely used to construct biosensors and drug delivery systems. − Exponential enrichment ligand phylogenetic techniques are an effective way to obtain aptamers. To date, many target-targeted aptamers have been screened, such as proteins, veterinary drugs, heavy metal ions, cells, and subcellular structures. − However, traditional aptamer screening methods have the disadvantages of long screening cycles and high screening efforts. Therefore, assisting aptamer screening with external forces can improve the efficiency of the isolation step and shorten the cycle time of aptamer screening to a certain extent.…”