Simultaneous Bilateral Spontaneous Pneumothorax Secondary to Metastatic Angiosarcoma of the Scalp: Report of a Case

Abstract

Angiosarcoma is a highly malignant neoplasm, which most often develops on the scalp or face of elderly people. Common distant metastatic sites include the lung, liver, lymph nodes, and skin. We report a case of angiosarcoma manifesting as simultaneous bilateral spontaneous pneumothorax secondary to pulmonary metastases in an 86-year-old man. The pneumothorax preceded the diagnosis of angiosarcoma. Chest computed tomography showed multiple thin-walled cavitary metastatic pulmonary lesions, which increased in size as new lesions appeared over the clinical course of several months. This case suggests that a finding of simultaneous bilateral spontaneous pneumothorax may indicate a serious parenchymal lung disorder.

Recurrent bilateral spontaneous pneumothorax secondary to lung adenocarcinoma with epidermal growth factor receptor mutation

“…Pneumothorax occurs most frequently with osteosarcomas, although it has been reported in other sarcomatous tumors and in tumors with an aggressive and necrotic nature . Metastatic pulmonary angiosarcomas, especially those arising from the scalp, frequently present with pneumothorax . SP as a complication of primary lung carcinoma is rare.…”

“…2 Metastatic pulmonary angiosarcomas, especially those arising from the scalp, frequently present with pneumothorax. [3][4][5] SP as a complication of primary lung carcinoma is rare. It is estimated that only 2% of all cases of SP coexist with malignant lung diseases, either primary or secondary.…”

Simultaneus bilateral spontaneus pneumothoraces: A Retrospective Analysis of 11 Cases

“…Spontan pnömotorakslar içinde eşzamanlı iki taraflı spontan pnömotoraks oranı birçok çalışmada %1'in altında gösterilirken, bazılarında da %3-8 olarak bildirilmektedir [7][8][9]. Esther ve ark.…”

Simultaneous bilateral spontaneous pneumothorax following high-dose chemotherapy and bone marrow transplantation for mantle cell lymphoma without evidence of pulmonary disease

“…The majority of cases had known lung lesion metastases or had a detectable lung lesion noted shortly after the SBSP occurred. The phenomenon has been reported in cases of metastatic sarcoma, trophoblastic tumor, non-seminomatous testicular cancer, and non-Hodgkin lymphoma [3][4][5][6][7][8][9][10] Sarcoma is most commonly associated with SBSP. One review examining 15 cases of SP after treatment with chemotherapy found an average time to develop SP after initiation of chemotherapy was 2-23 days [7].…”