Simultaneous Acquisition of T790M Mutation and SCLC Transformation during Targeted Therapy in EGFR-Mutated Lung Adenocarcinoma: A Rare Case Report
Tatsuya Yazaki,
Masanobu Kimoto,
Ayumi Minagawa
et al.
Abstract:Patient: Male, 66-year-old
Final Diagnosis: Combined small cell lung carcinoma
Symptoms: Cough
Clinical Procedure: —
Specialty: Oncology
Objective:
Unusual clinical course
Background:
Various resistance mechanisms of the epidermal growth factor receptor tyrosine kinase inhibitor (
EGFR
-TKI) have been reported, and approximately half of the cases show a T790M point mutation as resist… Show more
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