Simultaneous 19F–1H medium resolution NMR spectroscopy for online reaction monitoring

Rapid and simultaneous relaxometric methods to study paramagnetic ion complexes in solution: An alternative to spectrophotometry

“…Recently, medium resolution bench top spectrometers from 40 to 60 MHz (B 0 = 1 to 1.4 T) have been manufactured by several companies and are opening a new era for NMR routine analysis [5]. The medium resolution analyses are normally based in the frequency-domain spectrum, using chemical shift, spin-spin coupling and signal area, similar to high-resolution NMR analysis [6].…”

Online Monitoring of Polymerizations: Current Status

“…[50] Low-field or benchtop NMR spectroscopy is further commonly used for continuous monitoring of chemical reactions. [51,52] Guthausen and coworkers monitored the emulsion polymerization of nBA in batch. [53] Multiple setups are reported where NMR spectroscopy is coupled with a flow reactor to follow the reactions in real-time.…”

Monitoring of hydrogenation by benchtop NMR with parahydrogen‐induced polarization

“…Unlike Fourier‐transform infrared (FTIR), Raman, and ultraviolet (UV) spectroscopies, nuclear magnetic resonance (NMR) spectroscopy helps monitor chemical reactions while providing information on the reaction kinetics, speciation, time to completion, and yield without any specific requirement for the sample conditions. Although the use of real‐time NMR for monitoring reactions in situ is in its infancy by using a portable NMR spectrometer in the field, the trend is rapidly changing with technological improvements to make it increasingly practical. The NMR technique has gained particular research interest in pharmaceutical and chemical industries because it can be easily applied to the manufacturing system for chemical process control and for quality check of products to meet target specifications .…”