Simulation of heat exposure and damage to the eye lens in a neighborhood bakery

Sharon, N.; Bar‐Yoseph, P.; Bormusov, E.; Dovrat, A.

doi:10.1016/j.exer.2008.04.007

Cited by 22 publications

(17 citation statements)

References 16 publications

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“…The incubator was maintained at 37°C and filled with 95% air and 5% CO 2 . To determine whether there was any change in the intensity of the reflected ultrasound, the cells were treated with 1 ng/ml of human recombinant transforming growth factor-b1 (hTGF-b1) (R&D Systems, Inc.) for 1 and 3 days after reaching the confluent state by inverted microscopy [8]. The non-treated cells were harvested 3 days after reaching the confluent stage and were defined as the control [9].…”

Section: Tissue Preparationmentioning

confidence: 99%

Ultrasonic intensity microscopy for imaging of living cells

et al. 2009

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Section: Tissue Preparationmentioning

confidence: 99%

Ultrasonic intensity microscopy for imaging of living cells

et al. 2009

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“…Heys et al [11] exposed intact pig lenses to elevated temperature (50 • C) and found the protein changes associated with a progressive increase in lens stiffness as in presbyopia. Sharon et al [27] conducted lens organ culture system to analyze the catalase activities in lens epithelium. They found that even a short time exposure to high temperature caused optical damage to cultured lenses.…”

Section: Discussionmentioning

confidence: 99%

“…For modeling purpose, the opened eye is divided into six regions: cornea, aqueous humor, lens, vitreous humor, retina, and sclera. In several literatures [12,20,21,[25][26][27] choroid/retina/sclera were modeled as a single layer as sclera. We separated choroid/retina from sclera and assumed as a different layer for three reasons:…”

Section: Eye Geometry and Propertiesmentioning

confidence: 99%

Mathematical model of thermal effects of blinking in human eye

2015

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Blinking is regarded as the continuous interrupted eyelid closure or opening and its thermal effect will compromise between these two. During a blink, the heat loss via convection, radiation and tear evaporation from cornea is prevented, warm tear is layered across corneal surface and the vessels of the palpebral conjunctiva provide heat to anterior eye. In most of the thermal models in human eye that are found in literatures, effect of blinking is not included, simulation is carried out only in open eye. Thus, in this paper, thermal effects of blinking are investigated using one-dimensional finite element method in transient state case. The bio-heat transfer process is simulated during different blinking rates, lid closure and opening. The simulation is carried out using normal and extreme values of ambient temperatures, blood temperatures, evaporation rates, blood perfusion rates, and lens thermal conductivities. Blinking is found to increase corneal and lens temperature by 1.29 • C and 0.78 • C respectively when compared to open eye. The results obtained from this model are useful in predicting temperature distribution in different laser eye surgeries, hyperthermia and cryosurgery treatment of eyelid carcinoma, choroidal melanoma and can be used for diagnosing temperature-related diseases.

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“…Ahuva Dovrat at the Rappaprt Faculty of Medicine has been studying the effects of aging on the lens, using an in vitro experimental model, in which various conditions and factors can be applied and examined under critical conditions. Dovrat et al have thus investigated the mechanisms involved in heat damage to the eye lens, where workers are exposed to high environmental temperature (Sharon et al 2008). Bovine lenses were placed in specially designed culture containers for incubation of 11 to 15 days.…”

Section: The Aging Lensmentioning

confidence: 99%

Biogerontology research in Israel

Globerson

Reznick

2010

Biogerontology

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Studies on biogerontology in Israel are reviewed in relation to the academic and medical research setup, as well as to a variety of gerontological bodies that contribute to promotion of the research. Studies on the biology of aging are outlined with a view also on the relevance and possible applications to medicine. The various topics encompass longevity-associated genes, effects of calorie restriction, including studies on the experimental model of the alpha-MUPA mutant mouse, as well as basic issues regarding the central nervous system and skeletal tissues. Attention is paid also to stem cell biology as related to tissue repair in a variety of systems, and experiments performed on plants. Finally, a new insight into the theories on aging is viewed, as currently being pursued.

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Simulation of heat exposure and damage to the eye lens in a neighborhood bakery

Cited by 22 publications

References 16 publications

Ultrasonic intensity microscopy for imaging of living cells

Ultrasonic intensity microscopy for imaging of living cells

Mathematical model of thermal effects of blinking in human eye

Biogerontology research in Israel

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