Simulation of a Chaos-Like Irregular Neural Firing Pattern Based on Improved Deterministic Chay Model

Jiang, Zhongting; Wang, Dong; Sun, Jing; Shi, Hengyue; Shang, Huijie; Chen, Yuehui

doi:10.1007/978-3-030-22796-8_30

Cited by 1 publication

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Future work should continue to focus on ion channels. In our previous articles, we considered the mechanism of peak generation of nerve discharge, made reasonable assumptions about the probability of K + channel opening, and improved the CM [26]. That is, when the voltage of a single pulse reaches its peak, the K + channel will open completely at once.…”

Section: Discussionmentioning

confidence: 99%

Effect of potassium channel noise on nerve discharge based on the Chay model

Jiang

Wang

Shang

et al. 2020

THC

Self Cite

View full text Add to dashboard Cite

BACKGROUND: The nervous system senses and transmits information through the firing behavior of neurons, and this process is affected by various noises. However, in the previous study of the influence of noise on nerve discharge, the channel of some noise effects is not clear, and the difference from other noises was not examined. OBJECTIVE: To construct ion channel noise which is more biologically significant, and to clarify the basic characteristics of the random firing rhythm of neurons generated by different types of noise acting on ion channels. Method: Based on the dynamics of the ion channel, we constructed ion channel noise. We simulated the nerve discharge based on the Chay model of potassium ion channel noise, and used the nonlinear time series analysis method to measure the certainty and randomness of nerve discharge. RESULTS: In the Chay model with potassium ion noise, the chaotic rhythm defined by the original model could be effectively unified with the random rhythm simulated by the previous random Chay model into a periodic bifurcation process. CONCLUSION: This method clarified the influence of ion channel noise on nerve discharge, better understood the randomness of nerve discharge and provided a more reasonable explanation for the mechanism of nerve discharge.

show abstract

Section: Discussionmentioning

confidence: 99%