“…The computational inefficiency of microscopic simulators has mostly limited their use to what-if (i.e., scenario-based) analysis (as in, for instance, Bullock et al (2004), Ben-Akiva et al (2003)). Their use within simulation-based optimization (SO) algorithms is rare, and is limited to the use of first-order distributional information (Osorio and Selvam 2017, Osorio and Nanduri 2015a,b, Osorio and Chong 2015, Li, Abbas, Pasupathy and Head 2010, Stevanovic et al 2009, 2008, Branke et al 2007, Yun and Park 2006, Hale 2005, Joshi et al 1995. This paper proposes a methodology that enables the use of highresolution stochastic traffic simulators to efficiently address higher-order SO problems.…”