A kriging-based optimization algorithm is presented and applied to the design of a novel high-lift airfoil with a simply hinged, slotless flap and equipped with fluidic flow control. The position, orientation, and continuous-blowing characteristics of the actuator are set as design variables for the maximization of lift in landing conditions. Comparisons with a fully slotted reference configuration are presented and conclusions are drawn. In particular, it is found that a careful parameterization of the jet is capable of an efficient control strategy and leads to a complete reattachment of the flap flow, with considerable gains in lift and aerodynamic efficiency. A functional analysis of variance demonstrates the possibility of a dimensional reduction in the problem formulation and allows for a more in-depth analysis of the mechanisms governing separation management and alleviation in that particular case.freestream Mach number N = number of samples P = number of variables Re j = l ref -based Reynolds number VR = jet to local isentropic velocity ratio V inj = injection velocity V isentropic = isentropic boundary velocity V x = streamwise velocity V 1 = freestream velocity x inj = injection abscissa y = normalized first cell height = angle of attack = boundary-layer thickness flap = flap deflection angle inj = injection angle