Simulation and Optimization: A New Direction in Supercritical Technology Based Nanomedicine
Yulan Huang,
Yating Zheng,
Xiaowei Lu
et al.
Abstract:In recent years, nanomedicines prepared using supercritical technology have garnered widespread research attention due to their inherent attributes, including structural stability, high bioavailability, and commendable safety profiles. The preparation of these nanomedicines relies upon drug solubility and mixing efficiency within supercritical fluids (SCFs). Solubility is closely intertwined with operational parameters such as temperature and pressure while mixing efficiency is influenced not only by operation… Show more
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