Traditional oil seals are insufficient for the high-speed and bi-directional rotation of new energy electric vehicles. Therefore, we developed a Python program focusing on micro-groove pump seals and examined the unexplored non-contact oil–air biphasic internal end-face seals. Real gas effects were described using the virial and Lucas equations. We introduced an oil–air ratio to determine the equivalent density and viscosity of the two-phase fluid in the seal. Furthermore, we solved the compressible steady-state Reynolds equation using the finite difference method. Analysing the seal’s pumping mechanisms and the effects of operating parameters on sealing performance, we assessed 17 types of hydrodynamic grooves. The results demonstrate that inverse fir tree-like grooves perform well under typical sealing conditions. Under the conditions given in this study, the pumping rate of the optimal groove type compared to other groove types even reached 633.54%. In the oil–air biphasic state, the micro-groove pump seal exerts significant dynamic pressure on the sealing surface. Seal opening force increases with rotational velocity, oil–air ratio, and inlet pressure but decreases with temperature. The pumping rate first increases and then decreases with rotational velocity, increases with oil–air ratio and temperature, and then decreases with inlet pressure. Some special working points require consideration in sealing design. Our results provide insights into designing micro-grooved pumping seals for new energy electric vehicles.