Simulating the ultrafiltration of whey proteins isolate using a mixture model

Haribabu, Malavika; Dunstan, Dave E.; Martin, Gael M.; Davidson, Malcolm R.; Harvie, Dalton J. E.

doi:10.1016/j.memsci.2020.118388

Cited by 9 publications

(6 citation statements)

References 37 publications

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“…Although the four enzymes could catalyze whey protein cross‐linking, the relative flux levels were not at all increased compared to the control. It was assumed that many large proteins were deposited on the membrane surface forming tight cake resistance under transmembrane pressure, which made membrane filtration difficult (Haribabu et al., 2020). In this study, the TG + tyrosinase catalyzed whey protein cross‐linking could increase the membrane filtration efficiency.…”

Section: Resultsmentioning

confidence: 99%

The effect of composite enzyme catalysis whey protein cross‐linking on filtration performance

Wang

Ji‐yang

Qian

et al. 2021

Food Science & Nutrition

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In this study, enzymatic cross‐linked whey protein coupling ultrafiltration was used to reduce membrane fouling and increase whey protein recovery rate. The filtration efficiency and protein interaction with the membrane surface were investigated. The results showed that the protein recovery rate and relative flux of transglutaminase catalysis protein followed by tyrosinase each increased by approximately 30% during ultrafiltration. The total membrane resistance was reduced by approximately 20%. The shape of the transglutaminase and tyrosinase cross‐linked protein had somewhat spherical and cylindrical structure similar to an elongated shape based on fluorescence microscopy imaging, which indicated membrane resistance reduction. Fluorescence excitation–emission matrix spectroscopy (EEM) showed that the permeation peak intensities of transglutaminase followed by tyrosinase catalysis protein decreased sharply in the tryptophan and aromatic‐like protein fields, indicating that most protein was rejected after ultrafiltration. The repulsive interaction energy was increased between the cross‐linked proteins and membrane based on extended Derjaguin–Landau–Verwey–Overbeek (XDLVO) analysis.

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Section: Resultsmentioning

confidence: 99%

The effect of composite enzyme catalysis whey protein cross‐linking on filtration performance

Wang

Ji‐yang

Qian

et al. 2021

Food Science & Nutrition

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“…Multiphase mixture models are not restricted to classical industrial applications. Haribabu et al [9] used the mixture model to examine the filtration process of a whey protein. Milk is another example of a dispersed mixture, where water and oil represent the continuous and the dispersed phases, respectively.…”

Section: Introductionmentioning

confidence: 99%

Computational modelling of the separation of molten polymer blends by a centrifugal technique

Medvid¹,

Steiner²,

Irrenfried³

et al. 2023

Preprint

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Computational modelling of a centrifugal technique for separating binary mixtures of thermoplastic polymers in the molten state is presented. The technique may be useful for the recycling of polymeric materials. The study investigates the physical process of component separation due to the centrifugal force in a batch process, showing the potential of using a dispersed model for describing the complex mechanism underlying the technique. Given the long time scales of change of the flow field, the polymer melts are modelled as inelastic, shearthinning materials. The centrifugal force drives the component with the higher density to the outer region of an annular cross section occupied by the melt inside a rotating containment. The model system PET/LDPE is investigated in detail. The simulations allow to predict the process time needed for the separation. The simulations are the basis for studying a continuous process in a rotating tube.

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“…Those models have been used to predict fluxes, pressure profiles, concentration distributions, shear stresses, and mass transfer as well as accumulation phenomena. Respective models are available for different setups, such as dead-end modules [3,8,17,18], flat sheet cross-flow rigs [19,20], hollow fiber modules [7,21] and multistage SPTFF units [22,23]. In the last two decades, the description of the accumulation phenomena during UF developed from a static, mostly qualitative to a dynamic quantitative analysis in order to better understand the important process limitations resulting.…”

Section: Introductionmentioning

confidence: 99%

“…Recently, Aguirre-Montesdeoca et al [19] protein (BSA) and accompanying ions, they predicted the permeate flux, volume fractions of BSA on the membrane surface and the osmotic pressure difference over the membrane under different pH and ionic strengths in the feed solution. Haribabu et al [17] pointed out the importance to show the non-uniformity of parameters like local transmembrane pressure, flow velocity, and concentration at different positions of the membrane in the cross-flow filtration. They advised using a multi-dimensional numerical treatment instead of a one dimensional or area-averaged models.…”

Section: Introductionmentioning

confidence: 99%

Simulation-based evaluation of single pass continuous diafiltration with alternating permeate flow direction

Tan

Franzreb

2022

Separation and Purification Technology

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Simulating the ultrafiltration of whey proteins isolate using a mixture model

Cited by 9 publications

References 37 publications

The effect of composite enzyme catalysis whey protein cross‐linking on filtration performance

The effect of composite enzyme catalysis whey protein cross‐linking on filtration performance

Computational modelling of the separation of molten polymer blends by a centrifugal technique

Simulation-based evaluation of single pass continuous diafiltration with alternating permeate flow direction

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