Simulated Transurethral Resection Reaction in the Dog: Early Signs and Optimal Treatment

Symptomatology, Pathophysiology and Treatment of the Transurethral Resection of the Prostate Syndrome

“…Cessation of all fluid therapy was mandatory. While experimental (Drinker et al, 1963) and clinical (Kunin and Limbert, 1969) evidence has suggested that the use of hypertonic saline may be advisable, our experience indicates that it is best not to use this substance. The experimental evidence, unfortunately, was based on healthy animals with large cardiac reserves.…”

Fluid absorption and the ethanol monitoring method

“…The monitoring allows the anesthesiologist to begin the earliest possible treatment of acute cardiovascular fluid overload (vasodilators and/or assisted ventilation if breathing is affected), hyponatremia (hypertonic saline), and subacute hypovolemia (plasma volume expansion, preferably by a colloid) . Diuretics should not be given before the hemodynamic situation is stable and treatment with hypertonic saline has been initiated .…”

Ethanol‐glycine irrigating fluid for transurethral resection of the prostate in practice

“…However, hypertonic saline, which is a treatment originally proposed by Dr Harrison [6], operates as a diuretic and reverses, in contrast to frusemide, the underlying aberrations of electrolyte status and fluid distribution [17]. Scientific studies hold that reducing the bag height and administering frusemide are of no value and potentially dangerous, respectively, in preventing TUR syndrome, while hypertonic saline works as a remedy and improves survival [15,18,19]. The use of the ethanol method for the early detection of fluid absorption makes it possible to start treatment before severe TUR syndrome develops.…”