Simulated elliptical bioprosthetic valve deformation: Implications for asymmetric transcatheter valve deployment

Sun, Wei; Li, Kewei; Sirois, Eric

doi:10.1016/j.jbiomech.2010.08.010

Cited by 106 publications

(89 citation statements)

References 19 publications

(31 reference statements)

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“…Although in recent years numerical studies in this field have emerged, as far as the authors are aware, fluid-structure simulations of percutaneous valves are absent. Only structural 3,6,14,17,23,32,39 or fluid dynamics 3,13,31,37 studies have been carried out. This study used FSI simulations both in the in vitro durability testing and in the patient-specific set-up.…”

Section: Discussionmentioning

confidence: 99%

“…They can be related to the understanding of the mechanical behavior of the stented valve, the aortic root and the leaflet dynamics from a structural point of view 3,6,14,17,23,32,39 or to the hemodynamics inside the treated aortic root. 3,13,31,37 To the best of our knowledge, scientific publications which take into account both the mechanical and the fluid aspects in a coupled manner are absent. Fluid-structure interaction (FSI) is emerging as a powerful tool for the study of biomechanical problems, 33 and has been successfully applied for example to study the aortic root behavior in the presence of native valves.…”

Section: Introductionmentioning

confidence: 99%

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Fluid–Structure Interaction Model of a Percutaneous Aortic Valve: Comparison with an In Vitro Test and Feasibility Study in a Patient-Specific Case

Pott

Mazza

et al. 2015

Ann Biomed Eng

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Transcatheter aortic valve replacement (TAVR) represents an established recent technology in a high risk patient base. To better understand TAVR performance, a fluid-structure interaction (FSI) model of a self-expandable transcatheter aortic valve was proposed. After an in vitro durability experiment was done to test the valve, the FSI model was built to reproduce the experimental test. Lastly, the FSI model was used to simulate the virtual implant and performance in a patient-specific case. Results showed that the leaflet opening area during the cycle was similar to that of the in vitro test and the difference of the maximum leaflet opening between the two methodologies was of 0.42%. Furthermore, the FSI simulation quantified the pressure and velocity fields. The computed strain amplitudes in the stent frame showed that this distribution in the patient-specific case is highly affected by the aortic root anatomy, suggesting that the in vitro tests that follow standards might not be representative of the real behavior of the percutaneous valve. The patient-specific case also compared in vivo literature data on fast opening and closing characteristics of the aortic valve during systolic ejection. FSI simulations represent useful tools in determining design errors or optimization potentials before the fabrication of aortic valve prototypes and the performance of tests.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fluid–Structure Interaction Model of a Percutaneous Aortic Valve: Comparison with an In Vitro Test and Feasibility Study in a Patient-Specific Case

Pott

Mazza

et al. 2015

Ann Biomed Eng

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“…It is a thin pericardial bioprosthetic valve with similar design features to TAVs used commercially. This model has been extended previously to the development of elliptical valves, with eccentricities of 0.3, 0.5, and 0.68 and alignment of either the major or minor axis of the ellipse to a native commissure [7]. In the current study, the open configuration for each of these elliptical models was obtained using ABAQUS finite element simulation ( Fig.…”

Section: Methodsmentioning

confidence: 99%

Hemodynamic Impact of Transcatheter Aortic Valve Deployment Configuration

Sirois¹,

Li²,

Calderan³

et al. 2013

Journal of Medical Devices

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“…It commonly appeared in the shape of a triangle and ellipse [Zegdi et al (2008)]. Noncircular stent would lead to a higher stress on the leaflet [Gunning et al (2014); Sun et al (2010)]. …”

Section: Deformation Of Stentmentioning

confidence: 99%

Effect of Stent Designs on the Paravalvular Regurgitation of Transcatheter Aortic Valve Implantation

Chang

Liu

Zhong³

et al. 2019

Int. J. Comput. Methods

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Paravalvular aortic regurgitation (AR) significantly influences the outcome of transcatheter aortic valve implantation (TAVI). This study deals with the effect of stent design on AR after TAVI was evaluated by numerical simulations. Three different stents were implanted into the representative calcified human aortic root models. The excessively dense or a sparse outflow end would result in larger stent deformation indexes, higher stress of calcified plaques and aortic root, and larger gap between stent and aortic wall, and lead to serious paravalvular regurgitation. This study provides the guidance for design of transcatheter aortic valve.

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Simulated elliptical bioprosthetic valve deformation: Implications for asymmetric transcatheter valve deployment

Cited by 106 publications

References 19 publications

Fluid–Structure Interaction Model of a Percutaneous Aortic Valve: Comparison with an In Vitro Test and Feasibility Study in a Patient-Specific Case

Fluid–Structure Interaction Model of a Percutaneous Aortic Valve: Comparison with an In Vitro Test and Feasibility Study in a Patient-Specific Case

Hemodynamic Impact of Transcatheter Aortic Valve Deployment Configuration

Effect of Stent Designs on the Paravalvular Regurgitation of Transcatheter Aortic Valve Implantation

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