Simulated driving performance among daily and occasional cannabis users

Driving under the influence of drugs: Correlation between blood psychoactive drug concentrations and cognitive impairment. A narrative review taking into account forensic issues

“…Daily users drove slower after cannabis use as compared to the occasional use group and non-users. The study results do not conclusively establish that occasional users exhibit more driving impairment than daily users when both smoke cannabis ad libitum [ 93 ]. Moreover, it has been shown that inhalation of cannabis leads to a rapid increase in blood THC concentrations with a delayed decrease in vigilance and driving performance, more pronounced and lasting longer in occasional cannabis consumers than in chronic cannabis consumers [ 59 ].…”

Evidence of Health Effects Associated with Marijuana Use: A Comprehensive Public Health Review

“…Recent marijuana use/consumption by a driver increases the risk of a motor vehicle crash [170-172, 174, 182-188] Higher THC blood level increases the risk of a motor vehicle crash [173,178,180,189] Smoking more than 10 mg THC can lead to driving impairment [147,155,157,177,[190][191][192][193][194][195][196][197][198][199][200] Blood THC levels of impaired drivers are higher now than they were in the past [201] Orally ingesting more than 10 mg THC can lead driving impairment [146,147,153,155] Increased risk of driving impairment at blood THC as low as 2-5 ng/mL [155, 185,190,[202][203][204][205][206] Time to wait before driving Waiting at least 6 after smoking less than 18 mg allows driving impairment to resolve or nearly resolve [155,190,207] Waiting at least 6 h after smoking about 35 mg allows driving impairment to resolve or nearly resolve [157,192,196] Waiting at least 8 h after orally ingesting less than 18 mg allows driving impairment to resolve or nearly resolve [147,153,155,208] Table ...…”

How to read a paper on the short-term impairing effects of cannabis: A selective and critical review of the literature

“…A statistically-significant increase in SDLP from the use of cannabis was found only for the briefer car-following condition. In a study by Brooks-Russell et al (2021), two groups of subjects (occasional and regular users) drove on two types of roads (straight and curved). A statistically-significant increase in SDLP was found only for the occasional users on the straight road.…”

“…The complex algorithmic procedures used by the DRUID researchers to convert experimental results for drug impairment into proxy measures of crash risk were described in detail at the outset of the DRUID research program by Kruger et al (2008), who commented that their goal was to ‘Establish a method in order to interpret experimental results of driving studies as accident risks’. The researchers attempted to achieve that goal through using ‘information about one prominent substance – alcohol – as a reference for other substances’ (p. 8).…”