Simulated body fluid and water absorption effects on poly(methyl methacrylate)/hydroxyapatite denture base composites

Tham, W. L.; Chow, W. S.; Ishak, Z. A. Mohd

doi:10.3144/expresspolymlett.2010.66

Cited by 68 publications

(64 citation statements)

References 33 publications

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“…The hydroxyapatite-incorporated TPU20/PLA80 porous blend showed a high absorption capacity (10 times its own weight). This value is considered as a high capacity, while the other types of polymer-based scaffolds did not exhibit such a high water absorbability [21,22]. All the porous matrices demonstrated a good hydrophilicity.…”

Section: Water Absorption Capacity Wettabilitymentioning

confidence: 99%

Biphasic Polyurethane/Polylactide Sponges Doped with Nano-Hydroxyapatite (nHAp) Combined with Human Adipose-Derived Mesenchymal Stromal Stem Cells for Regenerative Medicine Applications

et al. 2016

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Cartilage and bone tissue injuries are common targets in regenerative medicine. The degeneration of cartilage tissue results in tissue loss with a limited ability to regenerate. However, the application of mesenchymal stem cells in the course of such condition makes it possible to manage this disorder by improving the structure of the remaining tissue and even stimulating its regeneration. Nevertheless, in the case of significant tissue loss, standard local injection of cell suspensions is insufficient, due to the low engraftment of transplanted cells. Introduction of mesenchymal stem cells on the surface of a compatible biomaterial can be a promising tool for inducing the regeneration by both retaining the cells at the desired site and filling the tissue gap. In order to obtain such a cell-biomaterial hybrid, we developed complex, biphasic polymer blend biomaterials composed of various polyurethane (PU)-to-polylactide (PLA) ratios, and doped with different concentrations of nano-hydroxyapatite (nHAp). We have determined the optimal blend composition and nano-hydroxyapatite concentration for adipose mesenchymal stem cells cultured on the biomaterial. We applied biological in vitro techniques, including cell viability assay, determination of oxidative stress factors level, osteogenic and chondrogenic differentiation potentials as well as cell proteomic analysis. We have shown that the optimal composition of biphasic scaffold was 20:80 of PU:PLA with 20% of nHAp for osteogenic differentiation, and 80:20 of PU:PLA with 10% of nHAp for chondrogenic differentiation, which suggest the optimal composition of final biphasic implant for regenerative medicine applications.

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Section: Water Absorption Capacity Wettabilitymentioning

confidence: 99%

Biphasic Polyurethane/Polylactide Sponges Doped with Nano-Hydroxyapatite (nHAp) Combined with Human Adipose-Derived Mesenchymal Stromal Stem Cells for Regenerative Medicine Applications

et al. 2016

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“…It increased the flexural strength as well as the flexural modulus of PMMA. 83 The interfacial interaction between HA filler and the PMMA matrix is enhanced by treatment with γ-MPS. 83,84 But a reduction in the flexural properties on water immersion was attributed to water's plasticizing effect, which weakens the bonding between the HA filler and the PMMA matrix.…”

Section: Mineralsmentioning

confidence: 99%

“…83 The interfacial interaction between HA filler and the PMMA matrix is enhanced by treatment with γ-MPS. 83,84 But a reduction in the flexural properties on water immersion was attributed to water's plasticizing effect, which weakens the bonding between the HA filler and the PMMA matrix. 83 The addition of HA NPs also increased both the fatigue and compression strength of PMMA resin in comparison with pure PMMA, 48 in addition to significant increase in thermal conductivity.…”

Section: Mineralsmentioning

confidence: 99%

PMMA denture base material enhancement: a review of fiber, filler, and nanofiller addition

Gad

Fouda

Al‐Harbi

et al. 2017

IJN

309

319

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This paper reviews acrylic denture base resin enhancement during the past few decades. Specific attention is given to the effect of fiber, filler, and nanofiller addition on poly(methyl methacrylate) (PMMA) properties. The review is based on scientific reviews, papers, and abstracts, as well as studies concerning the effect of additives, fibers, fillers, and reinforcement materials on PMMA, published between 1974 and 2016. Many studies have reported improvement of PMMA denture base material with the addition of fillers, fibers, nanofiller, and hybrid reinforcement. However, most of the studies were limited to in vitro investigations without bioactivity and clinical implications. Considering the findings of the review, there is no ideal denture base material, but the properties of PMMA could be improved with some modifications, especially with silanized nanoparticle addition and a hybrid reinforcement system.

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“…The weight gained of the ESO thermoset at any time t, M t as a result of water absorption was determined using Equation (5). The water diffusion coefficient (D) of ESO thermoset was determined using Equation (6) [13]:…”

Section: Water Absorption Of Eso Thermosetmentioning

confidence: 99%

Thermal properties, curing characteristics and water absorption of soybean oil-based thermoset

Tan¹,

Chow²

2011

Express Polym. Lett.

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Epoxidized soybean oil (ESO) was successfully thermal-cured by using methylhexahydrophthalic anhydride (MHHPA) curing agent, in the presence of tetraethylammonium bromide (TEAB) catalyst of varied concentration (0.3–0.8 phr). The polyesterification process of ESO thermoset was proven and supported by Fourier transforms infrared spectroscopy (FTIR) and gas chromatography-mass spectroscopy analysis (GC-MS). A possible chemical reaction of the MHHPA, TEAB and ESO was proposed based on the experimental work. Differential scanning calorimetry (DSC) and dynamic mechanical analysis (DMA) revealed that there is a positive relationship between the degree of conversion and crosslink density of ESO thermoset with TEAB concentration. The kinetics of water absorption of the ESO thermoset were found to conform to Fickian law behavior

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Simulated body fluid and water absorption effects on poly(methyl methacrylate)/hydroxyapatite denture base composites

Cited by 68 publications

References 33 publications

Biphasic Polyurethane/Polylactide Sponges Doped with Nano-Hydroxyapatite (nHAp) Combined with Human Adipose-Derived Mesenchymal Stromal Stem Cells for Regenerative Medicine Applications

Biphasic Polyurethane/Polylactide Sponges Doped with Nano-Hydroxyapatite (nHAp) Combined with Human Adipose-Derived Mesenchymal Stromal Stem Cells for Regenerative Medicine Applications

PMMA denture base material enhancement: a review of fiber, filler, and nanofiller addition

Thermal properties, curing characteristics and water absorption of soybean oil-based thermoset

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