Simplified Nomenclature and Projection Diagrams of Chiral Cubane Analogs

Abstract

A simplified nomenclature for chiral cubane analogs is proposed where analogs with a clockwise systematic continuous numbering of the cubane core are designated as ( C )-, and analogs with an anticlockwise continuous numbering of the cubane core are designated as ( A )-. This method is accurate, allows for the rapid conversion of the chemical name to a structure, and it eliminates the need to designate the stereochemistry of each of the 8 carbons of cubane.