Simplified
Helicobacter pylori
therapy for patients with penicillin allergy: a randomised controlled trial of vonoprazan-tetracycline dual therapy
Wen Gao,
Jianxiang Liu,
Xiaolei Wang
et al.
Abstract:Background and aimsThis study aimed to evaluate the efficacy and safety of vonoprazan and tetracycline (VT) dual therapy as first-line treatment forHelicobacter pyloriinfection in patients with penicillin allergy.MethodsIn this randomised controlled trial, treatment-naïve adults withH. pyloriinfection and penicillin allergy were randomised 1:1 to receive either open-label VT dual therapy (vonoprazan 20 mg two times per day+tetracycline 500 mg three times a day) or bismuth quadruple therapy (BQT; lansoprazole 3… Show more
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