Simplified and rapid determination of polychlorinated biphenyls, polybrominated diphenyl ethers, and polycyclic aromatic hydrocarbons in fish and shrimps integrated into a single method

Kalachová, Kamila; Pulkrabová, Jana; Drábová, Lucie; Čajka, Tomáš; Kocourek, Vladimı́r; Hajšlová, Jana

doi:10.1016/j.aca.2011.09.016

Cited by 91 publications

(46 citation statements)

References 28 publications

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“…The fish samples were prepared by a method described by Kalachova et al [28]. Briefly, 10 g of fish tissue homogenate (with surrogate BDE 37 and 13 C-CB 77 -10 ng absolutely) were mixed with 5 mL of distilled water and shaken vigorously with 10 mL of ethyl acetate in a polypropylene centrifuge tube for 1 min.…”

Section: Extraction and Clean-upmentioning

confidence: 99%

“…The fat determination and the choice of the silica minicolumn size according to the fish muscle fat content are described elsewhere [28]. Collected eluates were carefully evaporated using a vacuum rotary evaporator, and the residual solvents were removed under the gentle stream of nitrogen.…”

Section: Extraction and Clean-upmentioning

confidence: 99%

“…The main aim of the presented study was to develop and validate the GC×GC-TOFMS method for the simultaneous determination of PCBs, PBDEs, and PAHs in fish extracts prepared by the integral sample preparation procedure [28]. The focus of our experiments was to obtain the best chromatographic resolution and low LOQs for all target analytes.…”

Section: Introductionmentioning

confidence: 99%

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Implementation of comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry for the simultaneous determination of halogenated contaminants and polycyclic aromatic hydrocarbons in fish

et al. 2012

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In the presented study, comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC × GC-TOFMS) was shown to be a powerful tool for the simultaneous determination of various groups of contaminants including 18 polychlorinated biphenyls (PCBs), seven polybrominated diphenyl ethers (PBDEs), and 16 polycyclic aromatic hydrocarbons (PAHs). Since different groups of analytes (traditionally analyzed separately) were included into one instrumental method, significant time savings were achieved. Following the development of an integrated sample preparation procedure for an effective and rapid isolation of several groups of contaminants from fish tissue, the GC × GC-TOFMS instrumental method was optimized to obtain the best chromatographic resolution and low quantification limits (LOQs) of all target analytes in a complex mixture. Using large-volume programmable temperature vaporization, the following LOQs were achieved-PCBs, 0.01-0.25 μg/kg; PBDEs, 0.025-5 μg/kg; PAHs 0.025-0.5 μg/kg. Furthermore, several capillary column combinations (BPX5, BPX50, and Rxi-17Sil-ms in the first dimension and BPX5, BPX50, Rt-LC35, and HT8 in the second dimension) were tested during the experiments, and the optimal separation of all target analytes even of critical groups of PAHs (group (a): benz[a]anthracene, cyclopenta[cd]pyrene and chrysene; group (b): benzo[b]fluoranthene, benzo[j]fluoranthene and benzo[k]fluoranthene; group (c): dibenz[ah]anthracene, indeno[1,2,3-cd]pyrene and benzo[ghi]perylene) was observed on BPX5 × BPX50 column setup. Moreover, since the determination of target analytes was performed using TOFMS detector, further identification of other non-target compounds in real life samples was also feasible.

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Section: Extraction and Clean-upmentioning

confidence: 99%

Section: Extraction and Clean-upmentioning

confidence: 99%

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Implementation of comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry for the simultaneous determination of halogenated contaminants and polycyclic aromatic hydrocarbons in fish

et al. 2012

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“…At present, there is not a unique extraction technique and cleanup methods which eliminate completely the matrix effect. Nevertheless, the "Quick, Easy, Cheap, Effective, Rugged and Safe" (QuEChERS) methodologies have been applied in many laboratories, with good results and high recoveries, for several complex matrices extractions, such as: soil (Nanita et al, 2009;Rashid et al, 2010), biological samples (Kalachova et al, 2011), and food (Wilkowska and Marek, 2011;Hou et al, 2013). This method was created by Anastassiades and coworkers for the extraction of pesticides, which combines the isolation of pesticides from the complex matrix like food and the extract clean up (Anastassiades et al, 2003;Lehotay, 2007).…”

Section: Introductionmentioning

confidence: 99%

Analysis of tomato matrix effect in pesticide residue quantification through QuEChERS and single quadrupole GC/MS

Domínguez

Placencia

Cereceda

et al. 2014

Chilean J. Agric. Res.

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The detection of pesticide in tomato (Solanum lycopersicum L.) matrix using Gas Chromatography hyphenated to Mass Spectrometry detector (GC/MS) can affect the sensitivity of the analysis by enhancement or suppression of their chromatography response, the percentages of recoveries and leading to errors in the quantification of the pesticides. In this study, the matrix effect was investigated using nine pesticides, and "Quick, Easy, Cheap, Effective, Rugged and Safe" (QuEChERS)-GC/MS analytical technique was validated for pesticides multiresidue analysis. The matrix effect was determined using not statistical and statistical procedures including ANOVA, with similar results. Strong negative matrix effect was found for the pesticides trifluralin, 4,4'-DDT, and permethrin, resulting in the increment of the chromatogram background and a decrease in their detection responses. Contrary, an enhancement induced by the matrix presence was obtained for carbaryl and azinphos methyl, showing a positive medium matrix effect. While, dimethoate, simazine, 4,4'-DDE, and iprodione did not exhibit matrix effect. The detection limits (LOD) obtained, varied from 0.003 to 0.1 mg kg -1 . Reproducibility was less than 20% for each pesticide. Recoveries were found to be between 71% and 121%, except for dimethoate, carbaryl, and azinphos methyl which reached values lower than 70%. Recoveries relative standard deviations were less than 22%. Quechers-GC/MS technique was used for evaluation of fresh commercial tomatoes samples, detecting carbaryl in all of them, but in concentration levels lower than the maximum residue limits according to regulations of Codex.

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“…Nevertheless, the main challenge is the assurance of reliable analytical results of target contaminant determination considering their different physicochemical properties such as polarity, volatility and solubility in a wide range of solvents. The procedures of simultaneous preparation of food samples and determination of various contaminants therein have been developed initially for halogenated contaminants and polycyclic aromatic hydrocarbons in fish and shrimps (Kalachova et al 2011), polycyclic aromatic hydrocarbons (PAHs) and pesticides in fresh herbs (Sadowska-Rociek et al 2013), 3-monochloropropane-1,2-diol (3-MCPD) and acrylamide in different foods (Xu et al 2013), chloropropanols, acrylamide and ethyl carbamate in fermented products, flavouring and related foods (Mo et al 2014). However, foregoing studies are related mainly to compounds having similar polarity and lipophilicity.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Sample Preparation Method for Determination of 3-Monochloropropane-1,2-Diol and Polycyclic Aromatic Hydrocarbons in Different Foodstuffs

2016

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In the present study, a simultaneous sample preparation method for the determination of 3-monochloropropane-1,2-diol (3-MCPD) and polycyclic aromatic hydrocarbons (PAHs) in different foodstuffs has been evaluated. Sample preparation procedure involved acetonitrile extraction/ partitioning and cleanup by dispersive solid phase extraction with the final detection by gas chromatography coupled with mass spectrometry. The experiment demonstrated that freezing out of the sample extracts prior to dispersive solid phase extraction (d-SPE) cleanup step gave better results in removal of undesirable matrix constituents although with slightly lower recovery values. The addition of higher amount of MgSO 4 has contributed to increased values of polycyclic aromatic hydrocarbon recovery, in contrast to 3-MCPD for which the recoveries were insignificantly lower when MgSO 4 was added. Finally, a simultaneous chromatographic measurement has revealed that quantification of PAHs was not effective due to signal enhancement resulted from the presence of derivatisation products. However, the presented concept can be streamlined and an interesting analytical approach providing good validation parameter values: recoveries within the range 50-110 % for PAHs and 76-107 % for 3-MCPD, precision not exceeding 16.5 % (PAHs) and 7.7 % (3-MCPD) and quantification limits lower than 0.9 μg kg −1 for PAHs and 9.3 μg kg −1 for 3-MCPD.

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Simplified and rapid determination of polychlorinated biphenyls, polybrominated diphenyl ethers, and polycyclic aromatic hydrocarbons in fish and shrimps integrated into a single method

Cited by 91 publications

References 28 publications

Implementation of comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry for the simultaneous determination of halogenated contaminants and polycyclic aromatic hydrocarbons in fish

Implementation of comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry for the simultaneous determination of halogenated contaminants and polycyclic aromatic hydrocarbons in fish

Analysis of tomato matrix effect in pesticide residue quantification through QuEChERS and single quadrupole GC/MS

Simultaneous Sample Preparation Method for Determination of 3-Monochloropropane-1,2-Diol and Polycyclic Aromatic Hydrocarbons in Different Foodstuffs

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