Simple Synthesis and Functionalization of Iron Nanoparticles for Magnetic Resonance Imaging

Cheong, Soshan; Ferguson, Peter M.; Feindel, Kirk W.; Hermans, Ian F.; Callaghan, Paul T.; Meyer, C.; Slocombe, Angela; Su, Chia‐Hao; Cheng, Fong‐Yu; Yeh, Chen-Sheng; Ingham, Bridget; Toney, Michael F.; Tilley, Richard D.

doi:10.1002/anie.201100562

Cited by 155 publications

(93 citation statements)

References 31 publications

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“…In a recent study reported by Cheong et al [19], it was shown that Fe/FeOx core/shell NPs improve by a factor 2 the contrast in T 2 -weighted MR images of mice nodes compared with pure FeOx NPs. Interestingly, they allow for a much better in vivo detection of small tumours (1 -3 mm) at 1.5 T [19]. In vivo probing of small cancers (approx.…”

Section: Magnetic Resonance Imaging In Vivomentioning

confidence: 95%

New generation of magnetic and luminescent nanoparticles for in vivo real-time imaging

et al. 2013

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One contribution of 10 to a Theme Issue 'Molecular-, nano-and micro-devices for real-time in vivo sensing'. A new generation of optimized contrast agents is emerging, based on metallic nanoparticles (NPs) and semiconductor nanocrystals for, respectively, magnetic resonance imaging (MRI) and near-infrared (NIR) fluorescent imaging techniques. Compared with established contrast agents, such as iron oxide NPs or organic dyes, these NPs benefit from several advantages: their magnetic and optical properties can be tuned through size, shape and composition engineering, their efficiency can exceed by several orders of magnitude that of contrast agents clinically used, their surface can be modified to incorporate specific targeting agents and antifolding polymers to increase blood circulation time and tumour recognition, and they can possibly be integrated in complex architecture to yield multi-modal imaging agents. In this review, we will report the materials of choice based on the understanding of the basic physics of NIR and MRI techniques and their corresponding syntheses as NPs. Surface engineering, water transfer and specific targeting will be highlighted prior to their first use for in vivo realtime imaging. Highly efficient NPs that are safer and target specific are likely to enter clinical application in a near future.

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Section: Magnetic Resonance Imaging In Vivomentioning

confidence: 95%

New generation of magnetic and luminescent nanoparticles for in vivo real-time imaging

et al. 2013

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“…Since then, there has been substantial contribution to the development of biological labeling strategies that rely on the use of upconversion nanoparticles. Synthetic MNPs are emerging as versatile probes in biomedical applications, especially in the area of magnetic resonance imaging [130][131][132][133][134][135] and drug delivery [85,[136][137][138][139][140]. So,when considering the applications of the UCNPs-MNPs multi-functional nanocomposites, the strategies have been shown to be particularly attractive in multimodal imaging and magnetictargeted drug delivery.…”

Section: Applications Of Ucnps-mnps Nanocompositesmentioning

confidence: 99%

Upconversion Nanoparticle-Based Nanocomposites

Zhang

2014

Photon Upconversion Nanomaterials

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In recent years, the development of multi-functional nanomaterials with fantastic physical, chemical, and biological properties has become an attractive research topic, demonstrating high potential in biomedicine, catalysis, energy conversion, water treatment adsorbents, and so on. As one of the most important luminescence nanomaterials, upconversion nanoparticles (UCNPs) were also used to fabricate multi-functional nanocomposites (UCNPs-X). In this chapter, we summarize recent advanced upconversion nanoparticles-based nanocomposites, including UCNPs-mSiO 2 (mSiO 2 = mesoporous SiO 2 ), UCNPs-MNPs (MNPs = magnetic nanoparticles), UCNPs-metal, and UCNPs-semiconductor nanocomposites.

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“…Over the past few years, researchers have developed various types of nanoparticles for treatment of cancer [146][147][148][149][150][151]. Magnetic nanoparticles have received pervasive attention in medicine communities owing to their potentials in medical applications [146][147][148][149][150][151].…”

Section: C Nanoparticles Assembliesmentioning

confidence: 99%

“…Magnetic nanoparticles have received pervasive attention in medicine communities owing to their potentials in medical applications [146][147][148][149][150][151]. These applications associate closely with the unique magnetic properties of MNPs with comparable size to biologically important objects.…”

Section: C Nanoparticles Assembliesmentioning

confidence: 99%

Modification of Carbon Nanotubes as an Effective Solution for Cancer Therapy

Tavakolifard¹,

Biazar²

2016

Nano BioMed ENG

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Carbon nanotubes (CNT) as a new class of nano-materials hold great potential for various biomedical applications. Owing to their unusual properties, carbon nanotubes have been extensively employed in electronics, nanotechnology and optics, among others. In spite of the great potential of carbon nanotubes in various domains of biomedicine, ineffcient dispersion in aqueous solutions and biological activities in vivo are still disputable. One important and feasible route in a struggle to overcome these obstacles is modification of CNTs with organic compounds and polymers, which have been widely studied and play a crucial role in biological and biomedical fields, particularly in the cancer therapy. This review focuses on the breakthrough of the recently used methods to functionalize onto the surface of carbon nanotubes with multiple chemical species in order to produce anticancer drug delivery systems for biomedical applications.

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Simple Synthesis and Functionalization of Iron Nanoparticles for Magnetic Resonance Imaging

Abstract: International audienc

Cited by 155 publications

References 31 publications

New generation of magnetic and luminescent nanoparticles for in vivo real-time imaging

New generation of magnetic and luminescent nanoparticles for in vivo real-time imaging

Upconversion Nanoparticle-Based Nanocomposites

Modification of Carbon Nanotubes as an Effective Solution for Cancer Therapy

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